Egg Donation

After we evaluate your application, you may be contacted to schedule two appointments with our staff. First is an in-person physical and pelvic exam. Blood will be drawn to test for genetic disorders and infectious diseases. We may perform a Pap smear for cervical infectious disease testing.

A psychological screening will take place during the second appointment and includes an interview and written questionnaires. The results of the physical exam and psychological evaluation will determine if you’re a good match for egg donation, at which point you’ll be entered into our donor registry.

Hormone injections used to stimulate egg production may cause soreness at the injection site. The hormones may cause fatigue, cramping, mood swings, temporary water weight gain, or headaches. On rare occasions, you may temporarily develop ovarian hyper-stimulation syndrome (OHSS) which can cause a temporary shift in fluid levels in your ovaries, abdominal pain, and a general feeling of illness. Sometimes these symptoms go away on their own. The most severe cases require a hospital visit to drain fluid.

You’ll receive a hormone injection that greatly reduces the potential for OHSS but does not eliminate it entirely. During your initial visit, your providers will talk to you about OHSS and other potential complications.

Donating does not impact your production of eggs in the future or prevent you from having your own children. 

As an added layer of security, egg recipients provide donors with medical insurance coverage that covers egg cycle-related complications. This includes your exams and any medical treatment related only to your donation and that takes place immediately before, during, and after the donation. This coverage is complementary in addition to any insurance you may already have and lasts throughout the donation process and three months after you donate. You won’t need to change or discontinue your own insurance if you have it -- this additional coverage is provided at no cost to you. It cannot be used for other kinds of appointments or treatments.

Duke Fertility Center staff will file all necessary paperwork on your behalf and ensure you’re covered. Our team will provide you with a special insurance card that can be used for medical coverage during and after the donation process.

There is no timeline for how long you may wait between completing all your screenings and when an ideal match is made with a potential recipient. Matches are based on the preference of the recipient with guidance from Duke providers. The donation process doesn’t begin until there’s a match.

With the rise of publicly available genetic testing, lifelong, completely anonymous donation is difficult. However, we will not share your name or contact information with the egg recipient or future children unless you authorize it. When a match is made, you and/or the recipient can choose to remain anonymous during and after donation. Our goal is to respect your privacy as well as support you and the recipient family with common informational needs. A full explanation of the latest laws and practices around de-identifying information is provided in the donor consent form. We will also discuss this topic with you in depth during the screening process.

You may consider being part of the Donor Sibling Registry, a non-profit organization that provides donors and recipients a way to communicate anonymously. This can be helpful if you or the egg recipient have any questions after the donation related to your health history. Joining the Donor Sibling Registry is optional.