Metastatic Spine Cancer Treatment

When cancer spreads to the spine, the Duke Center for Brain and Spine Metastasis offers advanced and proven care. Our dedicated team of experts work to shrink or remove spine tumors while preserving your mobility and function. We strive to deliver the best-possible outcomes in the most compassionate way.

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About Metastatic Spine Cancer

Cancer that starts in one area of the body can metastasize, or spread, to the spine. Lung, breast, and prostate cancers are among those that most often spread to the spine.

Although metastatic spine cancer is typically considered advanced and may be life-threatening, we offer the full range of treatments to slow or stop the spread of cancer and reduce symptoms like pain.

New Patient Consultations Available Within 72 Hours

Our nurse navigator can also guide you through the process of seeking a second opinion for yourself or a loved one.

Diagnosing Spine Metastasis

Our team will conduct a series of comprehensive exams and tests to learn more about your unique condition and create a personalized treatment plan.

Imaging Scans

MRI, CT, PET, X-rays, bone scans, and angiography help accurately pinpoint the location, size, and stage of your spine tumor.

Biopsy

A small sample of your tumor may be removed and examined to confirm a diagnosis.

Our Locations

Duke Health offers locations throughout the Triangle. Find one near you.

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Surgical Treatments

Resection Surgery

Whenever possible, we use minimally invasive techniques and small incisions to remove (resect) all or part of the tumor. Surgery may also be an option for patients whose tumors return after treatment.

Spinal Cord Decompression and Stabilization

This procedure relieves pressure on the spinal cord. Successful decompression of the spinal cord may create space between the tumor and the spinal cord for the safe administration of high-dose radiation. If you have significant spinal cord compression or a collapsed vertebra, your surgeon may need to stabilize your spine using rods and screws.

Vertebroplasty/Kyphoplasty

When fractured or collapsed vertebrae result from a metastatic spine tumor, a surgical bone cement can be injected into the collapsed vertebra to stabilize the spine. The minimally invasive procedure is intended to relieve pain, reduce spinal deformity, and restore mobility. For certain people, we may be able to burn the tumor using minimally invasive techniques.

Nonsurgical Treatments

Stereotactic Radiosurgery

Despite the name, stereotactic radiosurgery does not require incisions. Instead, radiation oncologists focus narrow, high-dose radiation beams to destroy difficult-to-reach spine tumors. In some cases, only one treatment session is needed. Careful mapping and planning ensure the radiation targets cancer cells while sparing the healthy tissue, nerves, and blood vessels surrounding the tumor.

Immunotherapy

Immunotherapy drugs help your immune system identify and attack cancer cells while leaving healthy cells unharmed. New immunotherapy drugs may be available to eligible candidates through clinical trials.

Chemotherapy

Chemotherapy, given orally or by infusion into a vein, may be prescribed to kill cancer cells after surgery and/or radiation therapy.

Targeted Therapy

This treatment targets molecules inside your cells to stop cancer from growing and spreading, while sparing healthy cells. New targeted therapies may be available to eligible candidates through clinical trials.

Palliative Care

Palliative care focuses on preventing, managing, and relieving the symptoms of cancer and the side effects of cancer treatment. With services including pain management, symptom management, psychosocial support, and spiritual care, we help you and your loved ones clarify goals of treatment along the way. Research shows that people with cancer have better outcomes and live longer when supportive care is a regular part of treatment.

Rehabilitation Therapy

Rehabilitation will be an important part of your recovery. Our physical therapists and occupational therapists can help you strengthen your muscles, improve your mobility, or learn easier ways to perform everyday tasks.

Best Cancer Hospital in North Carolina

Where you receive your cancer care is important. Duke University Hospital is proud of our team and the exceptional care they provide. They are why our cancer program is the highest-ranked program in North Carolina, according to U.S. News & World Report for 2026–2027.

This page was medically reviewed on 08/17/2026 by
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