Temporal Lobe Surgery

Temporal Lobectomy, Limited Temporal Resection, Laser Ablation

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A temporal lobectomy and other epilepsy surgeries that target the temporal lobe can reduce or eliminate seizures that originate in specific areas of the brain. Duke Health neurosurgeons offer traditional and minimally invasive approaches to eliminate areas of the temporal lobe where seizures begin, with the overall aim of improving quality of life.

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Temporal Lobe Facts

  • Your brain’s temporal lobes are located on either side of the head, above your ears. 
     
  • Seizures often begin in the temporal lobe -- this is called temporal lobe epilepsy.
     
  • The temporal lobes are involved in functions like language and memory.
     
  • Surgical removal or laser treatment of temporal lobe tissue can be highly effective as an epilepsy treatment. Up to two-thirds of people experience seizure freedom, and those who still have seizures often experience reduced seizure frequency.
     
  • Temporal lobe surgeries carry a low risk of infection, stroke, and leakage of cerebrospinal fluid (fluid that surrounds the brain).
Our Locations

Temporal lobe surgery takes place in our main hospital in Durham, NC.

Temporal Lobe Surgery: Testing

Children and adults undergo a thorough surgical evaluation before a treatment is recommended. Learn more about:

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Temporal Lobe Surgery: What to Expect

Duke neurosurgeons are expertly equipped to perform temporal lobe surgery using a traditional open approach or minimally invasive laser approach. We listen to you and work as a team to choose your best option and minimize any impact on brain function.

Temporal Lobectomy
A neurosurgeon performs a craniotomy, which creates an opening in the skull to reach and remove a portion of the temporal lobe, usually the anterior (front) section.

To limit potential loss of function, doctors may remove a smaller section of the temporal lobe if your seizure focus is especially compact. Doctors call this a “limited temporal resection.”

After surgery, you’ll stay in the hospital for a few days. Most people return to normal activities in about six weeks.

Minimally Invasive Approach with Laser Ablation
A neurosurgeon drills one or two small holes, about the diameter of a pencil, into the skull. Using MRI guidance, a laser probe is passed through the holes to target and eliminate the brain tissue that initiates seizure activity.

This type of laser interstitial thermal therapy (LITT) may reduce your post-surgical hospital stay and speed recovery.

Cell Transplantation Clinical Trial

As a Duke patient, you may be eligible to receive an investigational epilepsy treatment involving cell transplantation into the temporal lobe. Less invasive than traditional epilepsy surgery, cell transplantation aims to reduce seizures originating from the temporal lobe by injecting cells called “cortical interneurons.”

Level 4 Epilepsy Center

As a Level 4 Epilepsy Center, Duke Health provides the highest level of diagnosis, medical, and surgical treatments for people with epilepsy. It is one reason why Duke University Hospital’s neurology and neurosurgery program is nationally ranked, and the highest-ranked program in North Carolina, according to U.S. News & World Report in 2025-2026.

This page was medically reviewed on 05/22/2025 by