Help End or Slow COVID-19: Join a Clinical Study, Trial, or Registry

Participate in Testing, Treatment, Vaccine Research

Tests, vaccines, and treatments will help slow and possibly put an end to COVID-19 and the impact it’s had on the world. Research, in the form of clinical trials and studies, can help make that happen as quickly as possible. Right now, scientists are working hard to:

  • Understand the virus and how it works in the body
  • Find and test treatments for people who have been infected
  • Prevent the spread of the disease more effectively
  • Identify and test vaccines
  • Assess the effect of the pandemic on people, communities, and society as a whole

Your help is needed to make these studies possible, whether you:

  • Are currently diagnosed with COVID-19 and are being treated in a hospital or recovering at home
  • Work in places that put you at high risk for the virus (for example, first responders and essential workers in grocery stores, pharmacies, nursing homes, hospitals, restaurants, etc.)
  • Have a medical condition that puts you at risk for becoming seriously ill if infected (for example, people with obesity, diabetes, heart disease, high blood pressure, etc.)
  • Are healthy and are at low risk for getting the virus or getting seriously ill if you do (for example, young, otherwise healthy adults)
COVID-19 Clinical Trials Directory

View all COVID-19 clinical trials currently enrolling or about to enroll through Duke investigators.

Your Options for Participating in Research

Depending on your situation, here’s how you can help further the current COVID-19 research.

If You Are Currently Diagnosed with or Suspect You Have COVID-19
Duke is participating in several COVID-19 research studies that are studying:

  • at-home symptom tracking
  • outpatient testing
  • inpatient treatment
  • outpatient treatment (coming soon)

You can help by joining the Pandemic Response Network’s Community Health Watch or a similar survey study to help you self-monitor for COVID-19 symptoms.

If You Had COVID-19
You may be eligible to participate in the Duke MESSI Study, which is collecting blood, saliva, and nasal samples from people (and their pets) who have been infected or live with someone who has been infected. This study will help our scientists and researchers learn more about the virus.

If you are fully recovered from your infection, you may be able to help someone else by donating COVID-19 convalescent plasma at a local blood bank like The Blood Connection or the American Red Cross.

Duke Vaccine and Trials Unit Vaccine Research Volunteer Registry
If you want to participate in a COVID-19 vaccine study, join the Duke Vaccine and Trials Unit Research Volunteer Registry. If you join the registry, we will contact you about vaccine research studies for which you may qualify.

If You Are an Essential Worker at High Risk for COVID-19
You can help by participating in vaccine trials. You are needed to help researchers learn if the vaccine effectively prevents infection in people who are exposed to the community on a regular basis. Vaccines are being tested through the Coronavirus Prevention Network. Duke investigators will be opening a Phase III vaccine trial shortly. Phase III trials are conducted to test the safety and effectiveness of a vaccine in a large population.

If You Work in a Health Care Facility (like a hospital, clinic, or nursing home)
Consider joining the 16,000+ people who have enrolled in the HERO Registry. It is for people who want to help scientists gather more evidence to aid in the prevention and treatment of COVID-19. People who work in health care facilities can also join vaccine trials.

If You Are at High Risk Because of a Medical Condition
You can join a symptom self-monitoring program like Duke's Pandemic Response Network’s Community Health Watch. This project encourages you to monitor yourself for symptoms related to COVID-19 and provides advice and guidance for what to do if you begin to experience symptoms. If you are interested in participating in a vaccine study, talk with your doctor first. They can help you determine whether it is safe for you to participate.

If You Are Healthy and at Low Risk for Serious COVID Illness
Consider joining the Duke Vaccine and Trials Unit Research Volunteer Registry or a similar database of people interested in learning more about COVID-19 clinical trials.

More Ways You Can Help

Learn about other ways you can help our community during this difficult time.