Duke Health Provider question
Let us work together as a team to help your child.
– John L. Lyles, MD

John L. Lyles, MD

Pediatric Gastroenterologist

Duke Health Provider question
Accepting New Patients
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Where I See Patients
Duke Children's Gastroenterology Creekstone - Durham, NC
Duke Children's Hospital & Health Center - Durham, NC
Board Certified
American Board of Pediatrics, Pediatric Gastroenterology
Let us work together as a team to help your child.
– John L. Lyles, MD

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About Me

I chose medicine because of my desire to help people live their healthiest lives. I chose pediatric gastroenterology because children and adolescents deserve the opportunity to grow and develop to their full potential. I especially love that this pediatric gastroenterology allows me to work with my hands through endoscopy and colonoscopy to diagnose and treat the conditions that we treat. Within my field, I am specifically interested in eosinophilic esophagitis and inflammatory bowel disease but enjoy seeing and treating everything from mouth to bottom.

Current Appointments and Affiliations
Languages I Speak
English

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Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.

Overall Provider Rating
4.51 out of 5
102 ratings, 7 reviews

Training and Education

Board Certification
American Board of Pediatrics, Pediatric Gastroenterology
Fellowship
Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center (Ohio), 2017-2020
Residency
Pediatrics, Children's National Medical Center (Washington, D.C.), 2014-2017
Education
MD, University of Alabama, 2014

Clinical Focus and Research

My Research Interests

I study eosinophilic esophagitis (EoE), an allergic condition affecting the esophagus, in pediatric patients. I am particularly interested in patients who have developed EoE very early in life and those who continue to report difficulty swallowing despite adequate treatment. Outside of EoE, I am interested in improving care delivered to patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis), specifically by maximizing the benefit they see when using certain medications like infliximab. I am also interested in applying and studying newer technologies such as transnasal endoscopy (EoE surveillance) and IBStim (disorders of the gut-brain axis) in the clinical setting.

Publications

Insurance Accepted

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.

    • Aetna Choice POS, Aetna Choice POS II
    • Aetna Elect Choice HMO, Aetna Open Access Elect Choice
    • Aetna Health Network Only, Aetna Health Network Option
    • Aetna HMO
    • Aetna Limited Benefit Insurance PPO
    • Aetna Managed Choice POS
    • Aetna Medicare Assure Plan (HMO D-SNP)
    • Aetna Medicare Eagle Plan (PPO)
    • Aetna Medicare Essential Plan (PPO)
    • Aetna Medicare Value Plan (HMO)
    • Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
    • Aetna Open Choice PPO
    • Aetna PCP Coordinated POS Plan
    • Aetna Quality Point of Service (QPOS)
    • Aetna Select HMO
    • Aetna Traditional Choice
    • Aetna Voluntary Indemnity Group Plan
    • Aetna Whole Health – Duke WakeMed WKCC
    • Aetna/CVS Health
    • Ambetter of North Carolina
    • Blue Advantage
    • Blue Medicare (HMO, PPO)*
    • Blue Options (123, PPO, HSA)
    • Blue Select
    • NC State Employees Health Plan
    • *Duke HomeCare and Hospice does not participate in the plan.

    • Cigna Behavioral Health (*Limited eligibility)
    • Cigna Choice Plus
    • Cigna Connect Individual Family Plan
    • Cigna Open Access
    • Cigna Open Access Plus
    • *Please call Cigna Behavioral Heath to see if the provider is participating in your plan.

    • Duke Basic
    • Duke Select
    • Experience Health Medicare Advantage (HMO) Plan
  • Gateway Health Alliance
  • Healthgram
    • Humana Choice (PPO)
    • Humana Choice - Medicare Advantage (PPO)
    • Humana ChoiceCare - Medicare Advantage (PPO)
    • Humana Gold Choice - Medicare Advantage (PFFS)
    • Humana Gold Plus - Medicare Advantage (HMO)
    • Humana Medicare Advantage Group Plan - NC State Retirees
  • MedCost
    • First Medicare Direct
    • Medicare Part A
    • Medicare Part B
    • AmeriHealth Caritas North Carolina
    • Carolina Complete Health
    • Healthy Blue
    • NC Medicaid Direct
    • WellCare of North Carolina
    • TRICARE Prime
    • TRICARE Prime Remote
    • TRICARE Select
    • AARP Medicare Advantage Plan 2 (HMO-POS)
    • AARP Medicare Complete (HMO, PPO)*
    • AARP Medicare Complete Essential (HMO)*
    • All Savers Alternate Funding
    • All Savers Fully Insured
    • United Healthcare (HMO, PPO, POS)
    • United Healthcare Charter/Charter Balance/Charter Plus
    • United Healthcare Choice/Choice Plus
    • United Healthcare Core/Core Essential
    • United Healthcare Navigate/Navigate Plus/Navigate Balanced
    • United Healthcare Option PPO
    • United Healthcare Passport Connect Choice/Choice Plus
    • United Healthcare Passport Connect Options PPO
    • United Healthcare Select/Select Plus
    • United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
    • United Medical Resources (UMR)
    • *Duke HomeCare and Hospice and mental health providers do not participate with the plan.

Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

External Relationships

This faculty member (or a member of their immediate family) has reported outside activities with the companies or institutions listed below. This information has been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts of interest.
  • GI Health Foundation
  • Sanofi and Regeneron Pharmaceuticals