Glenn J. Jaffe, MD
Ophthalmologist, Retinal Surgeon
My Locations
About Me
I’m a retina specialist who takes care of patients who have problems with the back of the eye. When a patient comes to see me, I like getting to know them and their history, so that I can tailor their treatment. My patients come from a variety of different backgrounds, so I find that I often learn as much from them as they do from me. Everybody has a different story and I very much like to learn about the patients to whom I provide care. Duke is a great place at which to work and from which to seek treatment because it’s a very collaborative institution. Everyone works together to do what’s best for the patient. Outside of work, I like to spend as much time as possible with my family. I also enjoy cooking, playing sports and watching sports.
- Robert Machemer M.D. Distinguished Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery 2013
- Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery 1998
- Chief, Division of Retinal Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery 2008
Call for an Appointment
Areas of Expertise
- Retinal Disease
- Uveitis
- Retinal Detachment
- Macular Holes
Ratings and Reviews
The ratings and reviews are based on patient responses to the overall provider rating question from the survey. The question reads: “Using any number from 0 to 10, where 0 is the worst provider possible and 10 is the best provider possible, what number would you use to rate this provider?” Responses are converted to a 5-point rating system and applied consistently to all providers. Learn more about our survey process. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.
Training and Education
In the News
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Clinical Focus and Research
I conduct research to develop intraocular sustained drug delivery systems, which are small implants that release medication over long time periods, that allow patients to avoid taking toxic medications or to receive painful injections. I'm also involved with projects to interpret images from large pharmaceutical company trials. We provide information from these studies that the FDA uses to decide whether or not to approve a drug used to treat an eye disease.
- Jaffe, G. J., P. Ashton, and P. A. Pearson. Preface, 2006.
- Jaffe, G. J., P. Ashton, and P. A. Pearson. Intraocular drug delivery, 2006.
- Lai, James C., Sandra S. Stinnett, and Glenn J. Jaffe. “B-scan ultrasonography for the detection of macular thickening.” Am J Ophthalmol 136, no. 1 (July 2003): 55–61. https://doi.org/10.1016/s0002-9394(02)02273-0.
- Stamer, W Daniel, Dean Bok, Jane Hu, Glenn J. Jaffe, and Brian S. McKay. “Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement.” Invest Ophthalmol Vis Sci 44, no. 6 (June 2003): 2803–8. https://doi.org/10.1167/iovs.03-0001.
- Yang, Ping, Brian S. McKay, Janice B. Allen, Wendy L. Roberts, and Glenn J. Jaffe. “Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells.” Invest Ophthalmol Vis Sci 44, no. 3 (March 2003): 1339–47. https://doi.org/10.1167/iovs.02-0878.
- Lin, P., and G. J. Jaffe. “Intermediate uveitis.” In Ryan S Retina Volume 1 3 Seventh Edition, 2:1672–83, 2022. https://doi.org/10.1016/B978-0-323-72213-1.00089-5.
- Lin, P., and G. J. Jaffe. “Intermediate uveitis.” In Retina Fifth Edition, 1405–14, 2012. https://doi.org/10.1016/B978-1-4557-0737-9.00079-5.
- Cahill, M. T., and G. J. Jaffe. “Intraocular sustained-release drug delivery in Uveitis.” In Intraocular Drug Delivery, 265–78, 2006.
- Wu, Zhichao, Srinivas R. Sadda, Thomas Ach, Barbara A. Blodi, Ferdinando Bottoni, Usha Chakravarthy, Emily Y. Chew, et al. “Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point-A Delphi Study: Classification of Atrophy Meetings Report 7.” In Ophthalmol Sci, 5:100777, 2025. https://doi.org/10.1016/j.xops.2025.100777.
- Dugel, Pravin U., Rishi P. Singh, Adrian Koh, Yuichiro Ogura, Georges Weissgerber, Kinfemichael Gedif, Glenn J. Jaffe, Ramin Tadayoni, Ursula Schmidt-Erfurth, and Frank G. Holz. “HAWK and HARRIER: Ninety-Six-Week Outcomes from the Phase 3 Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration.” In Ophthalmology, 128:89–99, 2021. https://doi.org/10.1016/j.ophtha.2020.06.028.
- Schneider, Eric W., and Glenn J. Jaffe. “BASELINE CHARACTERISTICS OF VITREOMACULAR TRACTION PROGRESSING TO FULL-THICKNESS MACULAR OR LAMELLAR HOLES IN THE PHASE III TRIALS OF ENZYMATIC VITREOLYSIS.” In Retina, 40:1579–84, 2020. https://doi.org/10.1097/IAE.0000000000002634.
Insurance Accepted
Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.
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Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Value Plan (HMO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
- Aetna/CVS Health
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Ambetter
- Ambetter of North Carolina
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Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
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*Duke HomeCare and Hospice does not participate in the plan.
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Cigna
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
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*Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
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Duke Group Plans
- Duke Basic
- Duke Select
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Experience Health
- Experience Health Medicare Advantage (HMO) Plan
- Gateway Health Alliance
- Healthgram
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Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
- MedCost
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Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
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NC Medicaid
- AmeriHealth Caritas North Carolina
- Carolina Complete Health
- NC Medicaid Direct
- UHC Community Plan
- WellCare of North Carolina
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TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
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United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)**
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
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*Duke HomeCare and Hospice and mental health providers do not participate with the plan.
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**Duke Health does not participate in UHC plans on the Health Insurance Marketplace.
Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.
External Relationships
- 4D Molecular Therapeutics
- Annexon Biosciences, Inc.
- BlueRock Therapeutics
- Boehringer Ingelheim
- EyePoint
- Genentech Roche
- Kriya Therapeutiucs
- Neurotech
- Ocular Therapeutix Inc.
- Regeneron Pharmaceuticals