Uveitis is a rare, complex condition that may result in eye pain, eye redness, blurred vision, light sensitivity, or floaters. The type of uveitis you have depends on which part of the eye is affected -- the front, middle, or the back. If not properly treated by an experienced ophthalmologist, uveitis may lead to glaucoma, cataracts, retinal swelling, or permanent vision impairment. Some common causes of the condition include infections, trauma, and autoimmune or inflammatory diseases.
Duke's team of uveitis specialists work to accurately diagnose your condition and provide comprehensive care to reduce inflammation and preserve your vision. At the same time, we help you manage the complications that are sometimes associated with uveitis treatments.
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To make an accurate diagnosis and to identify or exclude possible causes of uveitis, our specialists may perform several tests. In roughly 50% of cases, no associated systemic or infectious cause is detected.
Blood tests look for various inflammatory, autoimmune, and infectious conditions that may be causing uveitis.
A chest X-ray can help identify signs of tuberculosis or sarcoidosis (a disease that affects the lungs and lymph glands).
Fluid samples from the eye can sometimes help identify the cause of uveitis. An aqueous fluid sample may be obtained from the front of the eye during a clinic visit. If needed, a vitreous sample may be taken from the back of the eye during vitrectomy surgery, which is performed in the operating room.
Various types of retinal imaging, often combined with a dye injection (angiography), can help to confirm a diagnosis of uveitis and determine the extent of lesions and scarring. During follow-up, retinal imaging is performed to monitor the progression of uveitis and response to treatment.
Why Choose Duke
Advanced Training and Experience
The Duke uveitis clinic is staffed by ophthalmologists with advanced training and experience in managing uveitis, as well as experts in glaucoma, cataracts, and retinal disease. Our uveitis specialists work with rheumatologists to provide a comprehensive plan for managing medications and monitoring for complications. Joint uveitis-rheumatology appointments allow patients to receive a complete eye exam with monitoring of immunosuppressive medications at a single visit.
Infectious uveitis often requires specific treatment tailored to the infection. Duke’s uveitis specialists use specially compounded medications that are not readily available to treat different types of eye infections.
Learning to Manage Your Condition
Your care includes education about your condition, and access to our low vision rehabilitation program, which offers tools for living with impaired vision. Our dedicated social worker is also available to help you and your loved ones manage your care and maximize your quality of life.
Over 30 Years of Innovative Research
Duke’s uveitis specialists have been studying effective treatments for more than 30 years. We were instrumental in the development of a new steroid delivery system and were involved in the clinical trials that led to the 2016 FDA approval of the non-steroidal biologic drug Humira (adalimumab) to treat uveitis. We continue to actively participate in clinical trials and research to broaden our understanding of uveitis and effective treatments, and you may be a candidate to participate in these clinical trials.
When it comes to your care, you want the very best. Duke University Hospital’s ophthalmology program is ranked seventh in the nation and best in North Carolina by U.S. News & World Report for 2019–2020.