Steroid eye drops, eye injections, and oral or intravenous medications are often the first line of treatment for non-infectious uveitis. Sustained doses of steroids may also be delivered directly to the eye through a tiny, biodegradable implant that is injected into the gel of the eye. This provides longer-term control of inflammation. Because long-term use of steroids taken by mouth can have serious side effects, other types of medication may be recommended.
Drugs that suppress an overactive immune system may be recommended if long-term treatment is required to control chronic eye inflammation. These medications require frequent monitoring of blood work for potential side effects.
Biologics control inflammation by blocking specific proteins in the body. They do not carry the same side effects as steroids, and may sometimes be recommended for longer-term control of chronic inflammation. Adalimumab is the first approved biologic for the treatment of uveitis. It can be administered at home via an injection under the skin, typically every two weeks.