Carlos M. De Castro III, MD
Accepting New Patients
Duke Health Provider question
Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options.
– Carlos M. De Castro III, MD

Carlos M. De Castro III, MD

Hematologic Oncologist, Hematologist (Malignant)

Duke Health Provider question
Accepting New Patients
Call for an Appointment
Areas of Expertise
Where I See Patients
Duke Blood Cancer Center - Durham, NC
Duke Cancer Center - Durham, NC
Duke Hematologic Malignancies Clinic - Durham, NC
Board Certified
American Board of Internal Med, Internal Medicine
Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options.
– Carlos M. De Castro III, MD

About Me

I study disorders of the bone marrow and bone marrow failure syndromes. I also see some leukemias and lymphomas and other blood malignancies. Duke offers a very personalized, individualized level of care to each patient. Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options. We offer some of the latest treatment options that are available, usually in the setting of a clinical trial. If not, we offer the latest advancement in the field. When I was going through medical school, molecular biology was the new field. Everything was being described as a new cancer-causing gene. And to me that was so appealing – we’re going to figure out what causes cancer and new ways to treat it. That’s what really brought me into the hematology oncology world – things were being discovered that were new and exciting and hopefully would lead to new treatment options. Duke offers an extremely high standard of care. Though we’re not always successful and the disease sometimes wins, our goal is to give the patients the best possible care.

Current Appointments and Affiliations
Languages I Speak
English

Call for an Appointment

Areas of Expertise

  • Leukemia
  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Chronic Lymphocytic Leukemia
  • Chronic Myelogenous Leukemia
  • Hairy Cell Leukemia
  • Myelodysplastic Syndrome
  • Blastic Plasmacytoid Dendritic Cell Neoplasm

Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on DukeHealth.org.

Overall Provider Rating
4.87 out of 5
248 ratings, 33 reviews

Training and Education

Board Certification
American Board of Internal Med, Internal Medicine
Fellowship
Hematology/Oncology, Duke University Medical Center, 1988-1991
Residency
Internal Medicine, Parkland Memorial Hospital (Texas), 1985-1988
Education
MD, University of Texas Southwestern Medical School, 1985

Clinical Focus and Research

My Research Interests

I study disorders of the bone marrow and bone marrow failure syndromes.

Publications and Grants

Insurance Accepted

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.

    • Aetna Choice POS, Aetna Choice POS II
    • Aetna Elect Choice HMO, Aetna Open Access Elect Choice
    • Aetna Health Network Only, Aetna Health Network Option
    • Aetna HMO
    • Aetna Limited Benefit Insurance PPO
    • Aetna Managed Choice POS
    • Aetna Medicare Assure Plan (HMO D-SNP)
    • Aetna Medicare Eagle Plan (PPO)
    • Aetna Medicare Essential Plan (PPO)
    • Aetna Medicare Value Plan (HMO)
    • Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
    • Aetna Open Choice PPO
    • Aetna PCP Coordinated POS Plan
    • Aetna Quality Point of Service (QPOS)
    • Aetna Select HMO
    • Aetna Traditional Choice
    • Aetna Voluntary Indemnity Group Plan
    • Aetna Whole Health – Duke WakeMed WKCC
    • Aetna/CVS Health
    • Ambetter of North Carolina
    • Blue Advantage
    • Blue Medicare (HMO, PPO)*
    • Blue Options (123, PPO, HSA)
    • Blue Select
    • NC State Employees Health Plan
    • *Duke HomeCare and Hospice does not participate in the plan.

    • Cigna Behavioral Health (*Limited eligibility)
    • Cigna Choice Plus
    • Cigna Connect Individual Family Plan
    • Cigna Open Access
    • Cigna Open Access Plus
    • *Please call Cigna Behavioral Heath to see if the provider is participating in your plan.

    • Duke Basic
    • Duke Select
    • Experience Health Medicare Advantage (HMO) Plan
  • Gateway Health Alliance
  • Healthgram
    • Humana Choice (PPO)
    • Humana Choice - Medicare Advantage (PPO)
    • Humana ChoiceCare - Medicare Advantage (PPO)
    • Humana Gold Choice - Medicare Advantage (PFFS)
    • Humana Gold Plus - Medicare Advantage (HMO)
    • Humana Medicare Advantage Group Plan - NC State Retirees
  • MedCost
    • First Medicare Direct
    • Medicare Part A
    • Medicare Part B
    • AmeriHealth Caritas North Carolina
    • Carolina Complete Health
    • Healthy Blue
    • NC Medicaid Direct
    • WellCare of North Carolina
    • TRICARE Prime
    • TRICARE Prime Remote
    • TRICARE Select
    • AARP Medicare Advantage Plan 2 (HMO-POS)
    • AARP Medicare Complete (HMO, PPO)*
    • AARP Medicare Complete Essential (HMO)*
    • All Savers Alternate Funding
    • All Savers Fully Insured
    • United Healthcare (HMO, PPO, POS)
    • United Healthcare Charter/Charter Balance/Charter Plus
    • United Healthcare Choice/Choice Plus
    • United Healthcare Core/Core Essential
    • United Healthcare Navigate/Navigate Plus/Navigate Balanced
    • United Healthcare Option PPO
    • United Healthcare Passport Connect Choice/Choice Plus
    • United Healthcare Passport Connect Options PPO
    • United Healthcare Select/Select Plus
    • United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
    • United Medical Resources (UMR)
    • *Duke HomeCare and Hospice and mental health providers do not participate with the plan.

Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

External Relationships

This faculty member (or a member of their immediate family) has reported outside activities with the companies or institutions listed below. This information has been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts of interest.
  • Alexion Pharmaceuticals, Inc. a subsidiary of AstraZeneca
  • Apellis Pharmaceuticals
  • Genentech
  • Novartis
  • Omeros Pharmaceutical
  • Regeneron Pharmaceuticals