Duke Health Provider question
Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options.
– Carlos M. De Castro III, MD

Carlos M. De Castro III, MD

Cell Therapy and Hematologic Malignancies Specialist

Duke Health Provider question
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Board Certified
American Board of Internal Medicine, Hematology
American Board of Internal Medicine, Medical Oncology
American Board of Internal Medicine, Internal Medicine
Where I See Patients
Duke Cancer Center - Durham, NC
Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options.
– Carlos M. De Castro III, MD
My Locations
Duke Cancer Center
20 Duke Medicine Circle
Durham, NC 27710
Use My Current Location to calculate the distance to this facility.
This location is currently 5.5 miles from your current location.
About Me

I study disorders of the bone marrow and bone marrow failure syndromes. I also see some leukemias and lymphomas and other blood malignancies. Duke offers a very personalized, individualized level of care to each patient. Nobody is the same, so we take the whole patient, we listen to them, and we offer our best recommendations for treatment options. We offer some of the latest treatment options that are available, usually in the setting of a clinical trial. If not, we offer the latest advancement in the field. When I was going through medical school, molecular biology was the new field. Everything was being described as a new cancer-causing gene. And to me that was so appealing – we’re going to figure out what causes cancer and new ways to treat it. That’s what really brought me into the hematology oncology world – things were being discovered that were new and exciting and hopefully would lead to new treatment options. Duke offers an extremely high standard of care. Though we’re not always successful and the disease sometimes wins, our goal is to give the patients the best possible care.

Languages I Speak
English
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Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

Overall Provider Rating
4.85 out of 5
251 ratings, 50 reviews
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Training and Education
Board Certification
American Board of Internal Medicine, Hematology
American Board of Internal Medicine, Medical Oncology
American Board of Internal Medicine, Internal Medicine
Fellowship
Hematology/Oncology, Duke University Medical Center, 1988-1991
Residency
Internal Medicine, Parkland Memorial Hospital (Texas), 1985-1988
Education
MD, University of Texas Southwestern Medical School, 1985
Clinical Focus and Research
My Research Interests

I study disorders of the bone marrow and bone marrow failure syndromes.

Publications
View my publications on PubMed
Insurance Accepted

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.

  • Aetna
    • Aetna Choice POS, Aetna Choice POS II
    • Aetna Elect Choice HMO, Aetna Open Access Elect Choice
    • Aetna Health Network Only, Aetna Health Network Option
    • Aetna HMO
    • Aetna Limited Benefit Insurance PPO
    • Aetna Managed Choice POS
    • Aetna Medicare HMO Open Access
    • Aetna Medicare Plan (HMO, PPO)
    • Aetna Medicare Premier Plan (PPO)
    • Aetna Medicare Prime Plan (HMO, PPO)
    • Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Select, Aetna Open Access Managed Choice
    • Aetna Open Choice PPO
    • Aetna PCP Coordinated POS Plan
    • Aetna Quality Point of Service (QPOS)
    • Aetna Select HMO
    • Aetna Traditional Choice
    • Aetna Voluntary Indemnity Group Plan
    • Aetna Whole Health – Duke WakeMed WKCC
  • Ambetter
    • Ambetter of North Carolina
  • Blue Cross Blue Shield of NC
    • Blue Advantage
    • Blue Medicare (HMO, PPO)*
    • Blue Options (123, PPO, HSA)
    • Blue Select
    • NC State Employees Health Plan
    • *Duke HomeCare and Hospice does not participate in the plan.

  • CIGNA
    • Cigna Choice Plus
    • Cigna Open Access
    • Cigna Open Access Plus
  • Duke Group Plans
    • Duke Basic
    • Duke Select
  • First Health
  • Gateway Health Alliance
  • Gateway Health Plan
    • Gateway Health Medicare Assured Prime (HMO)
    • Gateway Health Medicare Assured Select (HMO)
  • Halifax Physician-Hospital Organization
  • Healthgram
  • Humana
    • Humana Choice (PPO)
    • Humana ChoiceCare (PPO)
    • Humana Gold Choice (PFFS)
    • Humana Gold Plus (HMO)
  • MedCost
  • Medicare
    • First Medicare Direct*
    • Medicare Part A
    • Medicare Part B
    • *This is for Wake County only.

  • MultiPlan / Private Healthcare Systems
  • NC Medicaid
    • NC Medicaid*
    • *Not all Duke locations and doctors participate in this plan. Please contact the location you will be visiting to determine what is accepted.

  • OneNet PPO
  • Optima Health
    • FAMIS
    • Optima Family Care (Medicaid HMO in VA)
    • Optima Individual & Family (On & Off Exchange Plans)
    • Optima Plus (PPO)
    • Optima Vantage (HMO)
  • TRICARE
    • TRICARE Extra*
    • TRICARE for Life*
    • TRICARE Prime*
    • TRICARE Prime Remote*
    • TRICARE Standard*
    • *Duke Primary Care does not participate with the plan.

  • United Healthcare
    • AARP Medicare Complete (HMO, PPO)
    • AARP Medicare Complete Essential (HMO)
    • All Savers Alternate Funding
    • All Savers Fully Insured
    • State Employee Health Plan (for retirees)
    • United Healthcare (HMO, PPO, POS)
    • United Healthcare Charter/Charter Balance/Charter Plus
    • United Healthcare Choice/Choice Plus
    • United Healthcare Core/Core Essential
    • United Healthcare Navigate/Navigate Plus/Navigate Balanced
    • United Healthcare of the River Valley
    • United Healthcare Option PPO
    • United Healthcare Options PPO with Harvard Pilgrim
    • United Healthcare Passport Connect Choice/Choice Plus
    • United Healthcare Passport Connect Options PPO
    • United Healthcare Select/Select Plus
    • United Medical Resources (UMR)

Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

Industry Relationships
This faculty member (or a member of their immediate family) has an outside financial interest with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
  • Apellis