Anna Mae E. Diehl, MD
Accepting New Patients
Duke Health Provider question
What has struck me about all of my patients is that they are very supportive of each other. They're very grateful for the help we can provide.
– Anna Mae E. Diehl, MD

Anna Mae E. Diehl, MD


Duke Health Provider question
Accepting New Patients
Call for an Appointment
Where I See Patients
Duke Gastroenterology Clinic - Clinic 2J - Durham, NC
Duke Pulmonary and Specialty Services Clinic - Clinic 2P - Durham, NC
Board Certified
American Board of Internal Med, Gastroenterology
American Board of Internal Med, Internal Medicine
What has struck me about all of my patients is that they are very supportive of each other. They're very grateful for the help we can provide.
– Anna Mae E. Diehl, MD

About Me

Liver disease is a disease that’s stigmatized. Many people are embarrassed to say they have liver disease, and that’s because liver disease is associated with alcoholism or drug abuse. But most people have liver disease that’s not related to those issues at all. People who smoke cigarettes get bad diseases, and we try not to stigmatize them. So it’s very difficult to be a patient with liver disease. They often feel isolated. But what has struck me about all of my patients is that they are very supportive of each other, and their families tend to be very supportive of them. They weather their condition with great grace, and they’re very grateful for the help we can provide. One of the things that distinguishes the gastroenterology division at Duke is that we have a very balanced faculty. Many programs specialize in one thing or another. Duke really covers the spectrum of gastrointestinal diseases. We have the breadth of general gastroenterologists, but we also have the sub-subspecialties.

Current Appointments and Affiliations
Languages I Speak
English, French

Call for an Appointment

Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score. Patients who see some types of providers receive a different version of the patient satisfaction survey. Those results are not available on

Overall Provider Rating
4.93 out of 5
40 ratings, 7 reviews

Training and Education

Board Certification
American Board of Internal Med, Gastroenterology
American Board of Internal Med, Internal Medicine
Gastroenterology, Johns Hopkins Hospital (Maryland), 1981-1984
Internal Medicine, Johns Hopkins Hospital (Maryland), 1978-1981
MD, Georgetown University School of Medicine (Washington, DC), 1978

Clinical Focus and Research

My Research Interests

I have devoted my career to studying how to improve recovery from liver injury. This is important for patients with all types of liver disease, because the two main causes of death from liver disease, cirrhosis and liver cancer, can develop when repair of liver damage is defective. My basic research laboratory showed that certain inflammatory factors help the liver to regenerate. In addition, we discovered that processes that form the liver during fetal development become reactivated in injured adult livers and help them to regenerate. These discoveries are leading to novel ways to diagnose and treat patients with liver disease so that cirrhosis and liver cancer can be prevented. I lead a team of scientists and doctors who are extending this work to patients. We have active clinical research programs in nonalcoholic fatty liver disease, sclerosing cholangitis and cirrhosis. In addition, I take care of patients with all kinds of liver disease.

Publications and Grants

Insurance Accepted

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.

    • Aetna Choice POS, Aetna Choice POS II
    • Aetna Elect Choice HMO, Aetna Open Access Elect Choice
    • Aetna Health Network Only, Aetna Health Network Option
    • Aetna HMO
    • Aetna Limited Benefit Insurance PPO
    • Aetna Managed Choice POS
    • Aetna Medicare Assure Plan (HMO D-SNP)
    • Aetna Medicare Eagle Plan (PPO)
    • Aetna Medicare Essential Plan (PPO)
    • Aetna Medicare Value Plan (HMO)
    • Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
    • Aetna Open Choice PPO
    • Aetna PCP Coordinated POS Plan
    • Aetna Quality Point of Service (QPOS)
    • Aetna Select HMO
    • Aetna Traditional Choice
    • Aetna Voluntary Indemnity Group Plan
    • Aetna Whole Health – Duke WakeMed WKCC
    • Aetna/CVS Health
    • Ambetter of North Carolina
    • Blue Advantage
    • Blue Medicare (HMO, PPO)*
    • Blue Options (123, PPO, HSA)
    • Blue Select
    • NC State Employees Health Plan
    • *Duke HomeCare and Hospice does not participate in the plan.

    • Cigna Behavioral Health (*Limited eligibility)
    • Cigna Choice Plus
    • Cigna Connect Individual Family Plan
    • Cigna Open Access
    • Cigna Open Access Plus
    • *Please call Cigna Behavioral Heath to see if the provider is participating in your plan.

    • Duke Basic
    • Duke Select
    • Experience Health Medicare Advantage (HMO) Plan
  • Gateway Health Alliance
  • Healthgram
    • Humana Choice (PPO)
    • Humana Choice - Medicare Advantage (PPO)
    • Humana ChoiceCare - Medicare Advantage (PPO)
    • Humana Gold Choice - Medicare Advantage (PFFS)
    • Humana Gold Plus - Medicare Advantage (HMO)
    • Humana Medicare Advantage Group Plan - NC State Retirees
  • MedCost
    • First Medicare Direct
    • Medicare Part A
    • Medicare Part B
    • AmeriHealth Caritas North Carolina
    • Carolina Complete Health
    • Healthy Blue
    • NC Medicaid Direct
    • WellCare of North Carolina
    • TRICARE Prime
    • TRICARE Prime Remote
    • TRICARE Select
    • AARP Medicare Advantage Plan 2 (HMO-POS)
    • AARP Medicare Complete (HMO, PPO)*
    • AARP Medicare Complete Essential (HMO)*
    • All Savers Alternate Funding
    • All Savers Fully Insured
    • United Healthcare (HMO, PPO, POS)
    • United Healthcare Charter/Charter Balance/Charter Plus
    • United Healthcare Choice/Choice Plus
    • United Healthcare Core/Core Essential
    • United Healthcare Navigate/Navigate Plus/Navigate Balanced
    • United Healthcare Option PPO
    • United Healthcare Passport Connect Choice/Choice Plus
    • United Healthcare Passport Connect Options PPO
    • United Healthcare Select/Select Plus
    • United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
    • United Medical Resources (UMR)
    • *Duke HomeCare and Hospice and mental health providers do not participate with the plan.

Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

External Relationships

This faculty member (or a member of their immediate family) has reported outside activities with the companies or institutions listed below. This information has been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts of interest.
  • American Association for Study of Liver Diseases and American Gastroenterological Association
  • American Association for the Study of Liver Disease (AASLD)
  • American Association for the Study of Liver Disease (AASLD)
  • Boehringer Ingleheim
  • International Society for Cells of Hepatic Sinusoid
  • Keystone Symposia
  • LA CATS (Lousiana CTSA)
  • NCI
  • Northern Ohio Alcohol Research Center
  • University of Louisville
  • University of Massachusetts Worster
  • University of Pittsburgh