Psycho-Oncology

A cancer diagnosis and treatment can profoundly affect the brain, giving rise to psychiatric conditions that deserve the same expert attention as your physical care. Depression, anxiety, delirium, and other psychiatric symptoms are common across every stage of cancer but often go unrecognized and untreated. Your cancer team can connect you with Duke Health psychiatrists who evaluate and treat people in Durham facing cancer.

 

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When Psycho-Oncology Can Help

New Diagnosis

A cancer diagnosis can trigger intense emotional responses, including shock, fear, and uncertainty. Once you are referred by your Duke oncologist, our psychiatrists assess you for depression, anxiety, and adjustment disorders, helping you and your oncology team understand how your mental health may affect your treatment decisions and overall care.

During Active Treatment

Cancer treatments including chemotherapy, immunotherapy, radiation, and surgery can cause or worsen psychiatric symptoms. Our team specializes in effects of cancer treatment such as depression, delirium, cognitive changes, and sleep disturbance, providing diagnosis and medication management tailored to the medical complexity of your care.

After Treatment

The end of active treatment can bring its own challenges, including fear of the cancer coming back, depression, and cognitive difficulties that last beyond treatment. Our psychiatrists work with you to evaluate and treat these ongoing symptoms, supporting your return to health and daily life.

Advanced Illness

When cancer can no longer be cured, mental health needs often intensify. Our team provides expert evaluation and treatment of depression, anxiety, delirium, and existential distress in the setting of advanced illness, working closely with your palliative care and oncology teams to support your quality of life and the people who care for you.

Our Locations

Duke Health offers locations throughout the Triangle. Find one near you.

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Treatment

Our psychiatrists work closely with your oncology team to provide expert care at every stage of your cancer experience. Your treatment may include one or more of the following:

Assessment

Symptoms of depression, anxiety, and cognitive changes such as memory loss, and problems focusing may overlap with the physical effects of cancer and its treatment. We evaluate your needs and recommend an appropriate treatment plan.

Medication Management

When medication is required, our team provides expert prescribing tailored to the demands of cancer treatment. We understand the interactions between psychiatric medications and cancer therapies, ensuring that your mental health treatment is safe, effective, and integrated with your overall medical care.

Supportive Services Available at Duke

Depending on your needs, we can connect you with a range of supportive services at Duke, including psychotherapy, palliative care, social work, and others.

Consistently Ranked Among the Nation’s Best Hospitals

Duke University Hospital is proud of our team and the exceptional care they provide. They are why we are recognized as the best hospital in North Carolina, and nationally ranked in 11 adult and 9 pediatric specialties by U.S. News & World Report for 2025–2026.

Why Choose Duke

Embedded Within Duke Cancer Institute

Our cancer services fall under the umbrella of the Duke Cancer Institute, which brings together the extensive resources of Duke University, Duke Health, and the Duke Comprehensive Cancer Center. We are committed to making innovative discoveries, developing new ways to prevent, diagnose, and treat cancer, and delivering those therapies in a patient- and family-centric way.

Specialized Expertise

Our team includes providers who specialize in cancer-related behavioral health care. This focused training ensures that your care is informed by a deep understanding of cancer, its treatments, and their effects on the brain and nervous system.

A Team Approach

We work closely with your oncology team as well as with Duke’s palliative care and supportive services programs, ensuring that we take a whole-person approach.

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This page was medically reviewed on 07/07/2026 by
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