Eosinophilic esophagitis occurs when a type of white blood cell called eosinophils accumulate in the esophagus and cause inflammation. While the exact cause of eosinophilic esophagitis is unknown, in some cases it may be caused by allergic sensitivity to certain foods. Eosinophils may also show up in the esophagus as a result of:
- Gastroesophageal reflux disease (GERD)
- Other types of esophagitis
- Inflammatory bowel disease (IBD)
- Infection
Children with EoE may experience trouble swallowing, vomiting, and other symptoms that can cause weight loss and failure to thrive. If eosinophilic esophagitis is left untreated, it can cause the esophagus to narrow, which can make swallowing even more difficult and lead to choking on food.