Amyotrophic lateral sclerosis (ALS)

Duke's ALS Center is one of 100 centers in the world dedicated to the diagnosis and treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. With a hopeful and optimistic approach, our team collaborates to maximize your quality of life and life expectancy.

Duke ALS clinic accepts the ice bucket challenge

Comprehensive care for ALS

Learning you may have amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, can be overwhelming. We understand, and we are here to help. When you first come to our ALS Center, you will have a comprehensive evaluation to confirm the diagnosis and to rule out the possibility that you have another condition. If we confirm your diagnosis, we provide a range of services from drug therapies and clinical trial access, to occupational, speech, nutrition, respiratory and physical therapy. Our goal is to help you live as full and normal a life as possible.

Choose Duke for your ALS treatment because we offer:

  • Shared decision making. We work closely together, and in partnership with you and your family, to identify the best treatment options and to make highly personalized recommendations for you.
  • Teamwork. At each visit, you and your family meet with various experts including neurologists, nurses, social workers, physical therapists, occupational therapists, respiratory therapists, nutritionists, speech pathologists, and clinic coordinators. This in-depth specialized care yields the best results in the treatment of ALS.
  • Clinical trial access. We have an active research program that often includes clinical trials for new medications to slow ALS, or improve symptoms associated with the condition.



Our doctors conduct a thorough evaluation to ensure that an ALS diagnosis is correct. As no one test can diagnose ALS, we base our diagnosis on a clinical examination and by ruling out all other diseases - a process known as a differential diagnosis. In addition to a thorough neurological examination, blood and lab tests, your evaluation may include:

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