Long History Treating Immune Disorders
Duke Children’s has spent more than 30 years conducting research that has advanced the treatment of life-threatening immune disorders. We continue to refine and improve the diagnosis and treatment options through our ongoing research and our work with organizations around the world.
Designations and Awards
We have been designated a Jeffery Modell Foundation Diagnostic and Research Center; we've also been named by the Immune Deficiency Foundation as a Center of Excellence. These designations recognize us for:
- providing the highest standard of care
- using innovation to advance treatments for immune deficiencies
- offering groundbreaking clinical trials and research for our patients
We are also internationally recognized for our research-based thymus transplant program, which treats children with DiGeorge syndrome.
American Lung Association Asthma Clinical Research Center
We are a designated American Lung Association Asthma Clinical Research Center, and we are one of 44 Centers in the U.S. and Canada that make up the Primary Immune Deficiency Treatment Consortium. We study why children are born with primary immune diseases and how we can improve the diagnosis and treatment of these conditions.
Access to Clinical Trials
Children may be eligible to participate in our ongoing clinical trials, which provide access to therapies that are not widely available. For example, we are studying ways to:
- improve the way bone marrow stem cell transplants are given to children with primary immune deficiencies
- offer new therapies for patients receiving immunoglobulin therapies
- perform advanced genetic testing to identify causes of immune deficiency
Excellent Patient Outcomes for SCID
We achieve excellent outcomes (overall survival of 75%) for patients with severe combined immunodeficiency (SCID) using T cell-depleted parental bone marrow stem cell transplants without pre-transplant chemotherapy.