Face masks are required at this location.

If you have or suspect you have been exposed to COVID-19, take these precautions before you seek care. If you have an appointment, learn about the safety measures in place at all Duke Health locations.

Duke Health Center at Southpoint

Duke Health Center at Southpoint houses multiple Duke Health clinics. To see which providers and services are offered at these clinics, please click on the individual clinic links below.

6301 Herndon Rd
Durham, NC 27713-6315

Clinics and Services at Duke Health Center at Southpoint

Duke Specialty Clinics at Duke Health Center at Southpoint include:

Services of Duke University Hospital Outpatient Departments include:

Monoclonal Antibodies Infusion Available Here

A one-time monoclonal antibodies is administered in our clinic, which is specially designed to safely care for people who are infected with COVID-19. If you think you have COVID-19 and are at high risk for severe infection, get tested and ask your doctor about monoclonal antibodies (mAbs) infusion treatment right away.

Preparing For Your Visit

Accessibility Services

We provide equal access for all people and offer a range of free accessibility services to patients and visitors who need them.

Interpreter Services

Free interpreter services can be provided for patients who prefer to communicate in a language other than English.


6301 Herndon Rd
Durham, NC 27713-6315

Public Transportation

Plan your trip to Duke Health Center at Southpoint through GoDurham bus route 12. The closest bus stop is Herndon Rd at Fayetteville Rd. If you have trouble accessing this route, visit GoDurham Access to check if you meet the ADA eligibility for Durham County’s accessible transit program.