Call your doctor before leaving home if you think you’ve been exposed to COVID-19 or have symptoms

Due to the presence of COVID-19 in our community, visitor restrictions are in place for all Duke clinics and hospitals. For your safety and the safety of others, we recommend patients do not bring a visitor to Duke clinics, if at all possible. If a visitor must accompany a patient, only one individual over 12 years of age is allowed. Patients and visitors will be screened for symptoms upon arrival. Individuals with flu-like symptoms are not allowed. View the complete list of Visitor Restrictions.

Effective immediately, Duke Health is prioritizing and rescheduling some non-emergent or non-critical surgeries, procedures, and appointments. Check our COVID-19 (Coronavirus) page for updates.

Duke Health Provider question
I enjoy interacting directly with patients and talking about the different options that are available to them.
– James L. Abbruzzese, MD

James L. Abbruzzese, MD

Medical Oncologist

Duke Health Provider question
Call for an Appointment
919-660-9673
New Patients
919-668-6688
Returning Patients
Board Certified
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Medical Oncology
Where I See Patients
Duke Cancer Center - Durham, NC
I enjoy interacting directly with patients and talking about the different options that are available to them.
– James L. Abbruzzese, MD
My Locations
20 Duke Medicine Circle
Durham, NC 27710
Use My Current Location to calculate the distance to this facility.
This location is currently 5.5 miles from your current location.
About Me

As a medical oncologist at the Duke Cancer Institute, my focus for many years has been on challenging cancer, particularly pancreatic cancer. We are learning and making progress, and with the collaborations, we build with radiation oncologists, surgeons, our imaging colleagues, and others, we're able to do things today that we could not do 10 years ago. I enjoy interacting directly with patients, particularly sharing with them what the pictures of their diseases look like – in my practice we use a lot of scans to show us what we're dealing with and then trying to relate that information to patients in an understandable way, and talk about the different options that are available to them. In my spare time, I like to run, work in my yard, and fish. After doing mostly saltwater fishing when I lived in Houston, I'm looking forward to exploring my freshwater options in this area.

Languages I Speak
English
Call for an Appointment
919-660-9673
New Patients
919-668-6688
Returning Patients
Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

Overall Provider Rating
4.87 out of 5
59 ratings, 11 reviews
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Training and Education
Board Certification
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Medical Oncology
Fellowship
Infectious Diseases, Johns Hopkins Hospital (Maryland), 1980-1981
Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School (Massachusetts), 1981-1982
Clinical Fellow, Medical Oncology Research, Dana-Farber Cancer Institute, Harvard Medical School (Massachusetts), 1982-1983
Residency
Internal Medicine, Johns Hopkins Hospital (Maryland), 1978-1981
Education
MD, University of Chicago Pritzker School of Medicine (Illinois), 1978
Clinical Focus and Research
My Research Interests

Novel therapeutics for pancreatic cancer.

Insurance Accepted

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below.

    • Aetna Choice POS, Aetna Choice POS II
    • Aetna Elect Choice HMO, Aetna Open Access Elect Choice
    • Aetna Health Network Only, Aetna Health Network Option
    • Aetna HMO
    • Aetna Limited Benefit Insurance PPO
    • Aetna Managed Choice POS
    • Aetna Medicare HMO Open Access
    • Aetna Medicare Plan (HMO, PPO)
    • Aetna Medicare Premier Plan (PPO)
    • Aetna Medicare Prime Plan (HMO, PPO)
    • Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Managed Choice
    • Aetna Open Choice PPO
    • Aetna PCP Coordinated POS Plan
    • Aetna Quality Point of Service (QPOS)
    • Aetna Select HMO
    • Aetna Traditional Choice
    • Aetna Voluntary Indemnity Group Plan
    • Aetna Whole Health – Duke WakeMed WKCC
    • Ambetter of North Carolina
    • Blue Advantage
    • Blue Medicare (HMO, PPO)*
    • Blue Options (123, PPO, HSA)
    • Blue Select
    • NC State Employees Health Plan
    • *Duke HomeCare and Hospice does not participate in the plan.

    • Cigna Choice Plus
    • Cigna Behavioral Health (*Limited eligibility)
    • Cigna Open Access
    • Cigna Open Access Plus
    • *Please call Cigna Behavioral Heath to see if the provider is participating in your plan.

    • Duke Basic
    • Duke Select
    • Experience Health Medicare Advantage (HMO) Plan
  • First Health
  • Gateway Health Alliance
    • Gateway Health Medicare Assured Prime (HMO)
    • Gateway Health Medicare Assured Select (HMO)
  • Halifax Physician-Hospital Organization
  • Healthgram
    • Humana Choice (PPO)
    • Humana ChoiceCare (PPO)
    • Humana Gold Choice (PFFS)
    • Humana Gold Plus (HMO)
  • MedCost
    • First Medicare Direct*
    • Medicare Part A
    • Medicare Part B
    • *This is for Wake County only.

  • MultiPlan / Private Healthcare Systems
    • NC Medicaid*
    • *Not all Duke locations and doctors participate in this plan. Please contact the location you will be visiting to determine what is accepted.

  • OneNet PPO
    • FAMIS*
    • Optima Family Care (Medicaid HMO in VA)*
    • Optima Individual & Family (On & Off Exchange Plans)
    • Optima Plus (PPO)
    • Optima Vantage (HMO)
    • *Duke Primary Care, Duke University Hospital, Duke Regional Hospital, and Duke Raleigh Hospital are not participating with this plan.

    • TRICARE Prime*
    • TRICARE Prime Remote*
    • TRICARE Select*
    • *Duke Primary Care is considered an authorized, non-network participating provider.

    • AARP Medicare Complete (HMO, PPO)*
    • AARP Medicare Complete Essential (HMO)*
    • All Savers Alternate Funding
    • All Savers Fully Insured
    • State Employee Health Plan (for retirees)
    • United Healthcare (HMO, PPO, POS)
    • United Healthcare Charter/Charter Balance/Charter Plus
    • United Healthcare Choice/Choice Plus
    • United Healthcare Core/Core Essential
    • United Healthcare Navigate/Navigate Plus/Navigate Balanced
    • United Healthcare of the River Valley
    • United Healthcare Option PPO
    • United Healthcare Options PPO with Harvard Pilgrim
    • United Healthcare Passport Connect Choice/Choice Plus
    • United Healthcare Passport Connect Options PPO
    • United Healthcare Select/Select Plus
    • United Medical Resources (UMR)
    • *Duke HomeCare and Hospice does not participate with the plan.

Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

External Relationships
This faculty member (or a member of their immediate family) has reported outside activities with the companies or institutions listed below. This information has been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts of interest.
  • American Association for Cancer Research
  • AstraZeneca
  • Bessor Pharma
  • Case Western Reserve University
  • Driver
  • Fujifilm
  • Halozyme Therapeutics, Inc.
  • Ipsen
  • Lustgarten Foundation
  • Moleculin Biotech Inc.
  • Pancreatic Cancer United Kingdom
  • PharmaCyte
  • Sun Biopharma
  • The University of North Carolina at Chapel Hill
  • University of California San Diego
  • University of Colorado Medical Center
  • University of Nebraska Medical Center