Spyre_Skyline-UC_Jawitz - Clinical Trial
What is the Purpose of this Study?
If you can join, you will be placed in Part A or Part B based on when you start. In Part A, you will get one of three study medicines: SPY001, SPY002, or SPY003. In Part B, you will get one of these medicines, a mix of two medicines, or a placebo, which does nothing. The study will last about 97 weeks, and you will have around 20 visits or phone calls. During these, doctors will do tests like blood draws, endoscopy with biopsy, heart checks, and x-rays.
Moderately to Severely Active Ulcerative Colitis
Who Can Participate in the Study?
To join this study, you must be 18 years or older and have ulcerative colitis that is moderate to severe. If you take steroid pills, your dose must stay the same for at least 2 weeks before getting the study medicine. You can join if other treatments for ulcerative colitis did not work well for you, stopped working, or caused bad side effects.
What is Involved?
This study wants to learn how three medicines, called SPY001, SPY002, and SPY003, affect people who have a sickness called ulcerative colitis. Ulcerative colitis is a disease that causes swelling and sores in the large intestine.
Study Details
