PRANCIR - Clinical Trial

What is the Purpose of this Study?

Participants will attend 7 visits at Duke Medical Center. They will first complete a training visit, then have 2 MRI visits about 1 to 4 weeks apart. Between the MRI visits, participants will attend up to 5 treatment visits on consecutive days. The study is testing a noninvasive treatment called transcranial magnetic stimulation (TMS) to see if it may help treat fibromyalgia.

What is the Condition Being Studied?

Fibromyalgia

Who Can Participate in the Study?

Participants may be able to join if they are women ages 18 to 65 with fibromyalgia that causes widespread pain, fatigue, and thinking or memory problems. They must be willing to receive noninvasive brain stimulation treatment, have two MRI brain scans, complete blood draws, sensory testing, and thinking games, and meet safety requirements for MRI scans and TMS treatment.

Age Group
Adults

What is Involved?

This study is looking at how changes in brain activity are related to chronic fibromyalgia pain. Researchers are testing a new treatment that aims to change brain activity to see if it can help reduce pain in people with fibromyalgia.

Study Details

Full Title
Pain & Reward Neuromodulation of CNS Circuits
Principal Investigator
Protocol Number
IRB: PRO00118676
NCT: NCT07525063
Phase
Phase N/A
ClinicalTrials.gov
Enrollment Status
Open for Enrollment
Support Duke Health research or honor a loved one with a tribute gift.
Giving to Duke Health