Open for Enrollment Soon
This study will open for enrollment soon. Please contact the study team for more information and check back frequently.
BARDA: JUST BREATHE_BP-ARDS-P2-00 (Acute Respiratory Distress Syndrome) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to test different drugs to see if they are safe and helpful for adults who are admitted in the hospital with acute respiratory distress syndrome (ARDS) compared to placebo (a substance that looks like a drug but does not contain an active drug).
What is the Condition Being Studied?
Acute Respiratory Distress Syndrome (ARDS)
Who Can Participate in the Study?
Adults ages 18+ who:
- Are admitted to the hospital with a diagnosis of ARDS
- Are not pregnant or nursing
For more information, contact the study team at kristy.johnson@duke.edu.
Age Group
Adults
What is Involved?
This study is called a platform study. A platform study is a study where several drugs are tested at the same time to figure out which drugs are most effective at helping resolve symptoms and restore people's health.
If you choose to join the study, you will get a random assignment to be treated with one of the following 4 options:
- vilobelimab; OR
- paridiprubart; OR
- bevacizumab (Avastin®); OR
- placebo
Study Details
Full Title
Phase 2 Clinical Platform Trial Investigating Multiple Therapeutic Options for the Treatment of Hospitalized Patients with Acute Respiratory Distress Syndrome (ARDS) BP-ARDS-P2-001_(Advarra IRB)
Principal Investigator
Christina E. Barkauskas, MD
Pulmonologist
Protocol Number
IRB:
PRO00118116
NCT:
NCT06703073
Phase
Phase II
ClinicalTrials.gov
View on ClinicalTrials.gov
Enrollment Status
Open for Enrollment Soon