BRCA HRT RCT Pilot (BRCA Mutations) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to better understand women's preferences for and concerns about hormone replacement. We want to learn from women who have had their fallopian tubes and ovaries removed due to BRCA1 and BRCA2 mutations.
What is the Condition Being Studied?
Hormone Replacement After Surgery Related to BRCA Mutations
Who Can Participate in the Study?
Women ages 19-49 who:
- Are diagnosed with a BRCA1 or BRCA2 mutation
- Are scheduled to have a risk reducing surgery with a gynecologic oncologist
- Do not have any history of cancer
For more information, contact the study team at amelia.lorenzo@duke.edu.
Age Group
Adults
What is Involved?
If you choose to join this study, you will fill out brief surveys at several time points before and after your surgery. You will also get a random assignment (like a coin flip) to either receive standard of care counseling about hormone replacement therapy or the standard of care plus an educational video.
Study Details
Full Title
Patient-centered education about hormone replacement therapy after risk-reducing salpingo-oophorectomy: a pilot randomized controlled trial
Principal Investigator
Laura J. Havrilesky, MD, MHSc
Gynecologic Oncologist
Protocol Number
IRB:
PRO00117007
NCT:
NCT06972719
Phase
Phase
N/A
ClinicalTrials.gov
View on ClinicalTrials.gov
Enrollment Status
Open for Enrollment