EXACT-2 CABG - Clinical Trial
What is the Purpose of this Study?
People in this study will have tests before they start. These tests include blood work, a heart check called an electrocardiogram, pictures of the heart, a chest x-ray, and answering questions on forms. If they can join, they will be put into one of two groups by chance. One group will get a medicine called XC001, and the other group will get a placebo. Both will be given as shots into the heart muscle during surgery. After surgery, there will be check-up visits at 2 weeks, and then at 1, 3, 6, and 12 months. These visits will include the same tests as before.
Coronary artery disease
Who Can Participate in the Study?
- Adults 18-80 years old
- Coronary artery disease needing surgical revascularization
- Increased likelihood of incomplete revascularization due to anatomical factors
- Has not had a heart attack or stroke withing the past 60 days
What is Involved?
The goal of this study is to find out if a medicine called XC001 works for people who have heart disease and need a surgery called coronary artery bypass. XC001 is made from a virus that has been changed so it can carry something called VEGF to the heart. VEGF helps new blood vessels grow. This can improve blood flow to the heart and help it stay healthy.
Study Details
