RUSH1F (Retinitis Pigmentosa in Usher Syndrome) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about mutations in the DNA of a gene called PCDH15. This mutation causes cells in the back of the eye to stop working (called "retinitis pigmentosa").

What is the Condition Being Studied?

Retinitis Pigmentosa in Usher Syndrome 1F

Who Can Participate in the Study?

Adults and children ages 8+ who:

- Are diagnosed with retinitis pigmentosa

- Have not had certain eye surgeries

For more information about who can be in this study, please contact the study team at

Age Group

What is Involved?

If you choose to join the study, you or your child will:

- Be enrolled in the study for about 4 and a half years

- Visit our clinic 6 times over these 4.5 years

At various visits, you or your child will complete some questionnaires and have eye and vision tests. This is a data collection study that has no experimental study procedures.

Study Details

Full Title
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F)
Principal Investigator
Protocol Number
IRB: PRO00111084
NCT: NCT04765345
Phase N/A
Enrollment Status
Open for Enrollment