CRYPTICS (Cardiopulmonary Bypass Surgery) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if an experimental product called cryopreserved platelets (CPP) can help control the bleeding that happens during and after cardiopulmonary bypass surgery. We want to see how well this product works in comparison to the standard therapy that is used to control bleeding during surgery, which is liquid stored platelets (LSP).

What is the Condition Being Studied?

Cardiopulmonary Bypass Surgery

Who Can Participate in the Study?

Adults who are scheduled or referred to have cardiopulmonary bypass surgery at Duke.

For more information about who can join this study, please contact the study team at dana.giangiacomo@duke.edu.

Age Group
Adults

What is Involved?

If you choose to join this study you will:

- Get a random assignment (like a coin flip) to either receive CPP or LSP during your surgery

- Have blood draws

- Have a follow-up phone call with the study team 30 days after your surgery

Study Details

Full Title
Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery (CRYPTICS)
Principal Investigator
Protocol Number
IRB: PRO00109067
NCT: NCT04709705
Phase
Phase II/III
ClinicalTrials.gov
Enrollment Status
Open for Enrollment