The Effects of Nicotine Levels on Pain - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about how nicotine levels in cigarettes impact the relationship between smoking and pain. We want to know if changing the nicotine content in cigarettes can alter any pain that smokers have. We hope the information from this study will lead to treatments that make it easier for smokers with pain to quit smoking.

What is the Condition Being Studied?

The Relationship Between Smoking, Nicotine Content, and Pain

Who Can Participate in the Study?

Adults ages 21-65 who:

- Smoke cigarettes every day

- Have had back pain for at least 3 months

For more information about who can join this study, please contact the study team at 919-907-9955.

Age Group
Adults

What is Involved?

If you choose to join this study, you will:

- Be assigned to a study group that may or may not lower the nicotine content of your cigarettes

- Visit our clinic in Durham 7 times

- Fill out surveys on a mobile phone app to monitor your pain, craving, and smoking behaviors

We will pay you for your time on the study. You can visit our website to learn more about this study and complete a survey to see if you might be eligible: https://redcap.duke.edu/redcap/surveys/?s=JNKYD4HM49P47CNX

Study Details

Full Title
Using very low nicotine content cigarettes disrupt the pain-smoking reinforcement cycle
Principal Investigator
Maggie Sweitzer
Protocol Number
IRB: PRO00108705
NCT: NCT05032755
Phase
Phase N/A
ClinicalTrials.gov
Enrollment Status
Open for Enrollment