Lung Health Cohort (Healthy Volunteers) - Clinical Trial

What is the Purpose of this Study?


We are doing this study to find out why some young adults have better lung function than others during the period of peak lung health (ages 25 to 35 years old) for most people. We want to learn how people's actions or exposures can affect lung function and risk of future lung disease. These factors might include smoking, vaping or diet and environmental exposures to pollution and allergens.

What is the Condition Being Studied?

Lung Function in Healthy Volunteers

Who Can Participate in the Study?

Key Eligibility

Adults ages 25-35 who:
- Are in general good health
- Are not pregnant
- Have never been diagnosed with cancer or heart disease

For more information about who can join this study, please contact the study team at or 919-479-0861.

Age Group

What is Involved?


If you choose to join this study, you will:
- Visit our clinic 1 time
- Have images taken of your lungs (CT scan), possibly on a different date from the clinic visit
- Have your lung function tested
- Give blood, nasal swab, and urine samples
- Answer questionnaires
- Wear an activity monitor for 7 days
- Keep a study diary for the 7 days you use the activity monitor
- Keep a vaping diary for the 7 days of activity monitoring (only if you vape)

After your clinic visit, you will have 5 brief, virtual visits with the study team. A team member will coach you on how to perform some breathing tests during these visits and then record your results.

We will follow up with you every 3-to-6 months for up to 5 years to see how you are doing and if there have been any changes to your health.

You can take a survey online to see if you might be eligible and to have a study team member contact you:

Study Details

Full Title
The American Lung Association Lung Health Cohort
Principal Investigator
Protocol Number
IRB: PRO00105522
Phase N/A
Enrollment Status
Open for Enrollment