X-PACT Immunolight (Breast Cancer, Head & Neck Cancer, Melanoma, and Sarcoma) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if an experimental drug and device system called X-PACT is a safe and effective treatment for various forms of cancer.

What is the Condition Being Studied?

Sarcoma, Breast Cancer, Melanoma, and Head & Neck Cancer

Who Can Participate in the Study?

Adults ages 18+ who:

- Have soft tissue sarcoma, melanoma, breast cancer, or head and neck cancer

- Still have cancer after treatment with the standard therapies

- Do not have any other treatment options left

For more information about who can join this study, please contact the study team at elizabeth.sachs@duke.edu

Age Group

What is Involved?

If you join this study, you will:

- Be injected with the study treatment (X-PACT) five times

- Give tumor tissue

- Have physical exams, blood draws, and urine tests

- Have a heart scan (ECG)

- Have imaging scans (X-Rays, MRI and/or CT)

Please visit https://www.immunolight.com/patients to learn more about the study treatment.

Study Details

Full Title
Phase 1 Study of X-PACT (X-ray Psoralen Activated Cancer Therapy) for Intra-tumoral Injection in Patients with Advanced Head and Neck Cancer, Breast Cancer, Soft Tissue Sarcoma or Melanoma
Principal Investigator
Orthopaedic Surgical Oncologist
Protocol Number
IRB: PRO00105022
NCT: NCT04389281
Phase I
Enrollment Status
Open for Enrollment