ESR1 peptides vaccine study (Breast Cancer) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if a new vaccine (ESR1 peptides) is safe and if they will help people with estrogen receptor positive (ER+) breast cancer.

What is the Condition Being Studied?

Breast Cancer

Who Can Participate in the Study?

Adults who:

  • Are diagnosed with breast cancer
  • Have completed chemotherapy or surgery
Age Group

What is Involved?

If you choose to join this study you will:

  • Get the study vaccine (ESR1 peptide)
  • Return to the Duke Cancer Center for follow-up visits 6-8 times over 10 weeks
  • Be contacted by phone every 12 weeks to see how you are doing
  • Have a skin biopsy (piece of skin will be taken) where the study vaccine was injected

Study Details

Full Title
A Phase I Study of Cancer Peptides plus GM-CSF and Adjuvant Following Completion of Prescribed Systemic Therapy of Estrogen Receptor Positive Breast Cancer
Principal Investigator
Protocol Number
IRB: PRO00104868
NCT: NCT04270149
Phase I
Enrollment Status
Open for Enrollment