ADRC Clinical Cohort (Alzheimer's Disease) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about Alzheimer's disease and other illnesses of aging (e.g., dementia, mild cognitive impairment [MCI], or other cognition disorders).

What is the Condition Being Studied?

People with and without a personal history or family history of Alzheimer's Disease

Who Can Participate in the Study?

Adults ages 45-80 who:

  • Are be able to read at a 6th grade level
  • Are willing to have an MRI scan and a lumbar puncture or PET scan
  • Have a study partner

For more information about who can be in this study, please contact the study team at or 919-660-2340.

Age Group

What is Involved?

This study will ask that you have a study partner. This is usually a family member that can answer questions about your day-to-day activities.

If you choose to join this study, you will:

  • Complete 3 study visits in 60 days and then yearly visits after that
  • Do brain and thinking tests
  • Have physical exams
  • Do memory tests
  • Complete medical and family history surveys
  • Get a brain MRI (image)
  • Have a lumbar puncture (spinal tap) or PET Scan

At your yearly follow-up visit, you will:

  • Do memory testing
  • Have a blood test

Study Details

Full Title
Duke Alzheimer's Disease Center Clinical Cohort (Duke as Single IRB of Record)
Principal Investigator
Geriatric Medicine Specialist
Protocol Number
IRB: PRO00103958
Phase N/A
Enrollment Status
Open for Enrollment