MRI following Stereotactic Radiosurgery for Brain Metastases - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if the study intervention (additional delayed MRI sequences) can tell the difference between radiation damage and tumor recurrence.

What is the Condition Being Studied?

Brain Metastases

Who Can Participate in the Study?

Adults ages 18+ who:

  • Have any metastatic solid tumor except small cell lung cancer or myeloma
  • Have at least 1 brain metastasis previously treated with Stereotactic Radiosurgery (SRS) with progression at the treated site(s)
  • Able to have Laser Interstitial Thermal Therapy (LITT)

*If you had whole brain radiotherapy before, that is allowed but not required

For more information about who can be in this study, please contact the study team.

Age Group

What is Involved?

If you choose to join this study, you will:

  • Have more images taken about 1 hour after your regular MRI
  • Let the study team to collect information from your medical record for 2 years

Study Details

Full Title
Diagnostic Accuracy of Delayed MRI Contrast Enhancement Characteristics and Radiation Necrosis Following Stereotactic Radiosurgery (SRS) for Brain Metastases
Principal Investigator
Radiation Oncologist
Protocol Number
IRB: PRO00103163
NCT: NCT04246879
Phase Pilot
Enrollment Status
Open for Enrollment