MitoQ (Asthma) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to see if an anti-oxidant pill called mitoquinol (mitoQ) might be helpful to control asthma.

What is the Condition Being Studied?

Asthma

Who Can Participate in the Study?

Adults age 18 and older who:
- Are diagnosed with asthma
- Do not smoke
- Are using a regular asthma controller (preventative) medication but still have asthma symptoms
- Have a BMI of 30 kg/m2 or higher
- Have not taken mitoquinol or a similar supplement like idebenone or co-enzyme Q10 in the last 8 weeks

For more information about who can join this study, please contact the study team at (919) 479-0861 or email DukeAirwayResearch@duke.edu.

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Take a daily dose of the study supplement (mitoQ) or a placebo (inactive substance), in pill form, for 12 weeks
- Visit our clinic 6 times over 14 weeks
- Have your lung function tested
- Give blood and urine samples
- Answer questionnaires
- Keep a daily diary of your asthma symptoms

You can take a survey online to see if you might be eligible and to have a study team member contact you: https://redcap.duke.edu/redcap/surveys/?s=AART8KMF8J

Study Details

Full Title
MitoQ for the treatment of Metabolic Dysfunction in Asthma
Principal Investigator
Pulmonologist
Protocol Number
IRB: PRO00102278
NCT: NCT04026711
Phase
Phase Pilot
ClinicalTrials.gov
Enrollment Status
Open for Enrollment
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698