MitoQ (Asthma) - Clinical Trial

What is the Purpose of this Study?

Treatment

We are doing this study to see if an anti-oxidant pill called mitoquinol (mitoQ) might be helpful to control asthma.

What is the Condition Being Studied?
Objective

Asthma

Who Can Participate in the Study?

Key Eligibility

Adults age 18 and older who:
- Are diagnosed with asthma
- Do not smoke
- Are using a regular asthma controller (preventative) medication but still have asthma symptoms
- Have a BMI of 30 kg/m2 or higher
- Have not taken mitoquinol or a similar supplement like idebenone or co-enzyme Q10 in the last 8 weeks

For more information about who can join this study, please contact the study team at (919) 479-0861 or email DukeAirwayResearch@duke.edu.

Age Group
Adults

What is Involved?

Description

If you choose to join this study, you will:
- Take a daily dose of the study supplement (mitoQ) or a placebo (inactive substance), in pill form, for 12 weeks
- Visit our clinic 6 times over 14 weeks
- Have your lung function tested
- Give blood and urine samples
- Answer questionnaires
- Keep a daily diary of your asthma symptoms

You can take a survey online to see if you might be eligible and to have a study team member contact you: https://redcap.duke.edu/redcap/surveys/?s=AART8KMF8J

Study Details

Full Title
MitoQ for the treatment of Metabolic Dysfunction in Asthma
Principal Investigator
Pulmonologist
Protocol Number
IRB: PRO00102278
NCT: NCT04026711
Phase
Phase Pilot
ClinicalTrials.gov
Enrollment Status
Open for Enrollment