Genetic Study for SCD and CHD (Heart Disease) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families.

Some conditions that we are looking at are:

-Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) such as hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy

-Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast), such as long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, short QT syndrome

-Sudden cardiac arrest or unexplained sudden death (heart stops suddenly), including sudden infant death syndrome (SIDS)

What is the Condition Being Studied?

Children and adults with unexplained sudden death or heart disease that was diagnosed before the age of 40 years old

Who Can Participate in the Study?

- Infants

- Children

- Adults, 40 and under

Age Group
Adults, Children

What is Involved?

If you choose to join this study, you will:

-Give a blood sample (must be able to travel to Duke for this)

-We may also ask family members to join the study to learn more about a disease running in the family.

For more information about who can be in this study, please contact the study team at

Study Details

Full Title
The Genetic and Molecular Basis of Sudden Cardiac Death-Predisposing Diseases and Congenital Heart Conditions
Principal Investigator
Protocol Number
IRB: PRO00094341
Phase N/A
Enrollment Status
Open for Enrollment