APEC1621 Pediatric MATCH Study - Clinical Trial

We are doing this study to see if different study drugs or drug combinations that target specific genetic changes found in some cancers will shrink the tumor and/or prolong the time to progression.

Solid tumors, non-Hodgkin lymphomas, sarcoma, CNS tumors

Children and adults with recurrent solid tumors, lymphoma, and CNS tumors who:
- Are aged 12 months to less than 21 years of age
- Have no uncontrolled infection
- Have had a prior solid organ transplant

If you choose to join this study, you will:
- Have tumor tissue from a biopsy sent to a lab for genetic testing
-- If the tumor tissue has a genetic change that is targeted by one or more of the study drugs being tested in this study, you may be assigned to that study.