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TMIST Mammography Study - Clinical Trial

What is the Purpose of this Study?

We are doing this study to compare two different screening mammography methods in pre- and post-menopausal women to understand whether one method is better than the other at finding life-threatening breast cancers

What is the Condition Being Studied?

Breast cancer.

Who Can Participate in the Study?

Women aged 45 to 74

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Be randomized (like the flip of a coin) to screening with Tomosynthesis Mammography (TM) or Digital Mammography (DM).

The frequency and number of screening mammograms will vary with your menopausal status and whether you have breast cancer risk factors.
-- All premenopausal women will have annual screening.

-- Postmenopausal women will have screening every 2 years unless they have any specific risk factors.

- Have either three-dimensional (3D) Tomosynthesis Mammography or two-dimensional (2D) Digital Mammography.

-- Get screened every year for four more years - for a total of five mammograms, or
-- Every other year - for a total of three mammograms.

- Be followed for 4.5 to 8 years.

Study Details

Full Title
EA1151: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Principal Investigator
Breast Imaging Specialist
Protocol Number
IRB:PRO00086885
NCT:NCT03233191
Phase
Phase III
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
studyrecruitment@duke.edu
or
919-681-5698