Chief, Pediatric Ophthalmology and Strabismus Service

• Ophthalmology / Pediatric Ophthalmology and Strabismus Service
• Pediatrics / Ophthalmology
• Ophthalmology / Glaucoma Service

Address:
DUMC 3802
Durham, NC 27710

Appointment Telephone:
919-681-3937

Fax Telephone:
919-684-6096

• MD, Harvard Medical School (Massachusetts), 1985

• Ophthalmology, Massachusetts Eye and Ear Infirmary, 1986-1989

• Pediatric Ophthalmology, Children's Hospital Boston (Massachusetts), 1989-1990
• Glaucoma, Duke Eye Center, 1990-1992

Clinical Interests:
Congenital and childhood glaucoma, strabismus, congenital cataracts, retinopathy of prematurity, ocular motility disorders due to cranial nerve palsies

Research Interests:
My current research interests include:

Childhood glaucomas - With a large referral practice of children with pediatric glaucomas of all types, Freedman is evaluating existing and new management strategies for treating refractory congenital and childhood glaucomas, including the use of pharmacologic agents, as well as modification of surgical interventions. Freedman has an on-going  collaboration with Duke colleagues to study the genetics of pediatric glaucoma.  In addition to an active clinical research program, she regularly lectures and directs workshop at national meetings aimed at educating other ophthalmologists about current strategies and controversies in managing children with refractory glaucoma.

Retinopathy of Prematurity - Freedman is the principal investigator at the Duke-UNC Center for an NIH-sponsored, multi-center trial to evaluate early treatment for retinopathy of prematurity. The goal of this effort is to optimize the timing of laser intervention for vision-threatening retinopathy of prematurity. Together with colleague David Wallace, she provides eye care and treatment to the many premature children who graduate from the Neonatal Intensive Care units at DUHS. Freedman and Wallace are involved in clinical research involving the computerized evaluation of retinal blood vessels in ROP.  Freedman and Wallace collaborate with Cynthia Toth and her Duke research team in applying the new imaging technique of Spectral Domain Optical Coherence Tomography to image children with retinopathy of prematurity and other retinal disorders.

Strabismus associated with macular translocation surgery - Together with Cynthia Toth, Freedman continues to surgically treat the cyclotorsion and strabismus resulting from macular translocation surgery. She has developed and published on new extraocular muscle surgical techniques to deal with this problem.

Representative Publications:
Yanovitch TL, Freedman SF, Wallace DK. Vascular dilation and tortuosity in plus disease. Arch Ophthalmol. 2009 Jan;127(1):112-3. (2009) Abstract

Yanovitch TL, Enyedi LB, Schotthoeffer EO, Freedman SF. Travoprost in children: adverse effects and intraocular pressure response. J AAPOS. 2009 Feb;13(1):91-3. (2009) Abstract

Johnston SC, Wallace DK, Freedman SF, Yanovitch TL, Zhao Z. Tortuosity of arterioles and venules in quantifying plus disease. J AAPOS. 2009 Apr;13(2):181-5. (2009) Abstract

El-Dairi MA, Asrani SG, Enyedi LB, Freedman SF. Optical coherence tomography in the eyes of normal children. Arch Ophthalmol. 2009 Jan;127(1):50-8. (2009) Abstract

Chong GT, Farsiu S, Freedman SF, Sarin N, Koreishi AF, Izatt JA, Toth CA. Abnormal foveal morphology in ocular albinism imaged with spectral-domain optical coherence tomography. Arch Ophthalmol. 2009 Jan;127(1):37-44. (2009) Abstract

Wallace DK, Quinn GE, Freedman SF, Chiang MF. Agreement among pediatric ophthalmologists in diagnosing plus and pre-plus disease in retinopathy of prematurity. J AAPOS. 2008 Aug;12(4):352-6. (2008) Abstract

Kemper AR, Freedman SF, Wallace DK. Retinopathy of prematurity care: patterns of care and workforce analysis. J AAPOS. 2008 Aug;12(4):344-8. (2008) Abstract

Freedman SF. Central corneal thickness in children--does it help or hinder our evaluation of eyes at risk for glaucoma? J AAPOS. 2008 Feb;12(1):1-2. (2008) Abstract

Ahmad S, Wallace DK, Freedman SF, Zhao Z. Computer-assisted assessment of plus disease in retinopathy of prematurity using video indirect ophthalmoscopy images. Retina. 2008 Nov-Dec;28(10):1458-62. (2008) Abstract

Wallace DK, Zhao Z, Freedman SF. A pilot study using "ROPtool" to quantify plus disease in retinopathy of prematurity. J AAPOS. 2007 Aug;11(4):381-7. (2007) Abstract

Wallace DK, Freedman SF, Zhao Z, Jung SH. Accuracy of ROPtool vs individual examiners in assessing retinal vascular tortuosity. Arch Ophthalmol. 2007 Nov;125(11):1523-30. (2007) Abstract

O'malley Schotthoefer E, Yanovitch TL, Freedman SF. Aqueous drainage device surgery in refractory pediatric glaucomas: I. Long-term outcomes. J AAPOS. 2007 Oct 15. (2007) Abstract

O'Malley Schotthoefer E, Yanovitch TL, Freedman SF. Aqueous drainage device surgery in refractory pediatric glaucoma: II. Ocular motility consequence. J AAPOS. 2007 Oct 16. (2007) Abstract

Muir KW, Duncan L, Enyedi LB, Wallace DK, Freedman SF. Central corneal thickness: congenital cataracts and aphakia. Am J Ophthalmol. 2007 Oct;144(4):502-6. (2007) Abstract

Holgado S, Toth CA, Freedman SF. Fixation switch and diplopia after full macular translocation surgery. J AAPOS. 2007 Apr;11(2):114-9. (2007) Abstract

El-Dairi MA, Holgado S, O'Donnell T, Buckley EG, Asrani S, Freedman SF. Optical coherence tomography as a tool for monitoring pediatric pseudotumor cerebri. J AAPOS. 2007 Dec;11(6):564-70. (2007) Abstract

Al-Haddad CE, Freedman SF. Endoscopic laser cyclophotocoagulation in pediatric glaucoma with corneal opacities. J AAPOS. 2007 Feb;11(1):23-8. (2007) Abstract

Trigler L, Proia AD, Freedman SF. Fibrovascular ingrowth as a cause of Ahmed glaucoma valve failure in children. Am J Ophthalmol. 2006 Feb;141(2):388-9. (2006) Abstract

Muir KW, Duncan L, Enyedi LB, Stinnett SS, Freedman SF. Central corneal thickness in children: stability over time. Am J Ophthalmol. 2006 May;141(5):955-7. (2006) Abstract

Muir KW, Duncan L, Enyedi LB, Freedman SF. Central corneal thickness in children: Racial differences (black vs. white) and correlation with measured intraocular pressure. J Glaucoma. 2006 Dec;15(6):520-3. (2006) Abstract

Holgado S, Enyedi LB, Toth CA, Freedman SF. Extraocular muscle surgery for extorsion after macular translocation surgery new surgical technique and clinical management. Ophthalmology. 2006 Jan;113(1):63-9. (2006) Abstract

Trigler L, Weaver RG Jr, O'Neil JW, Barondes MJ, Freedman SF. Case series of angle-closure glaucoma after laser treatment for retinopathy of prematurity. J AAPOS. 2005 Feb;9(1):17-21. (2005) Abstract

Tesser R, Hess DB, Freedman SF. Combined intraocular lens implantation and glaucoma implant (tube shunt) surgery in pediatric patients: a case series. J AAPOS. 2005 Aug;9(4):330-5. (2005) Abstract

Hess DB, Asrani SG, Bhide MG, Enyedi LB, Stinnett SS, Freedman SF. Macular and retinal nerve fiber layer analysis of normal and glaucomatous eyes in children using optical coherence tomography. Am J Ophthalmol. 2005 Mar;139(3):509-17. (2005) Abstract

Cahill MT, Stinnett SS, Banks AD, Freedman SF, Toth CA. Quality of life after macular translocation with 360 degrees peripheral retinectomy for age-related macular degeneration. Ophthalmology. 2005 Jan;112(1):144-51. (2005) Abstract

Muir KW, Jin J, Freedman SF. Central corneal thickness and its relationship to intraocular pressure in children. Ophthalmology. 2004 Dec;111(12):2220-3. (2004) Abstract

Freedman SF, Holgado S, Enyedi LB, Toth CA. Management of ocular torsion and diplopia after macular translocation for age-related macular degeneration: prospective clinical study. Am J Ophthalmol. 2003 Oct;136(4):640-8. (2003) Abstract

Freedman SF, Gearinger MD, Enyedi LB, Holgado S, Toth CA. Measurement of ocular torsion after macular translocation: disc fovea angle and Maddox rod. J AAPOS. 2003 Apr;7(2):103-7. (2003) Abstract

Dawn AG, Freedman SF, Lee PP, Enyedi LB. Parents' expectations regarding their children's eye care: interview results. Am J Ophthalmol. 2003 Nov;136(5):797-804. (2003) Abstract

Cahill MT, Freedman SF, Toth CA. Macular translocation with 360 degrees peripheral retinectomy for geographic atrophy. Arch Ophthalmol. 2003 Jan;121(1):132-3. (2003) Abstract

Freedman SF, Rojas M, Toth CA. Strabismus surgery for large-angle cyclotorsion after macular translocation surgery. J AAPOS. 2002 Jun;6(3):154-62. (2002) Abstract

Freedman SF, Rodriguez-Rosa RE, Rojas MC, Enyedi LB. Goniotomy for glaucoma secondary to chronic childhood uveitis. Am J Ophthalmol. 2002 May;133(5):617-21. (2002) Abstract

Enyedi LB, Freedman SF. Latanoprost for the treatment of pediatric glaucoma. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S129-32. (2002) Abstract

Toth CA, Freedman SF. Macular translocation with 360-degree peripheral retinectomy impact of technique and surgical experience on visual outcomes. Retina. 2001;21(4):293-303. (2001) Abstract

Enyedi LB, Freedman SF. Safety and efficacy of brimonidine in children with glaucoma. J AAPOS. 2001 Oct;5(5):281-4. (2001) Abstract

Beck AD, Freedman SF. Trabeculectomy with mitomycin-C in pediatric glaucomas. Ophthalmology. 2001 May;108(5):835-7. (2001) Abstract

Freedman SF, Seaber JH, Buckley EG, Enyedi LB, Toth CA. Combined superior oblique muscle recession and inferior oblique muscle advancement and transposition for cyclotorsion associated with macular translocation surgery. J AAPOS. 2000 Apr;4(2):75-83. (2000) Abstract

Freedman SF, McCormick K, Cox TA. Mitomycin C-augumented trabeculectomy with postoperative wound modulation in pediatric glaucoma. J AAPOS. 1999 Apr;3(2):117-24. (1999) Abstract

Enyedi LB, Freedman SF, Buckley EG. The effectiveness of latanoprost for the treatment of pediatric glaucoma. J AAPOS. 1999 Feb;3(1):33-9. (1999) Abstract

Englert JA, Freedman SF, Cox TA. The Ahmed valve in refractory pediatric glaucoma. Am J Ophthalmol. 1999 Jan;127(1):34-42. (1999) Abstract

Bock CJ Jr, Buckley EG, Freedman SF. Combined resection and recession of a single rectus muscle for the treatment of incomitant strabismus. J AAPOS. 1999 Oct;3(5):263-8. (1999) Abstract

Wallace DK, Kylstra JA, Greenman DB, Freedman SF. Significance of isolated neovascular tufts ("popcorn") in retinopathy of prematurity. J AAPOS. 1998 Feb;2(1):52-6. (1998) Abstract

Wagle NS, Freedman SF, Buckley EG, Davis JS, Biglan AW. Long-term outcome of cyclocryotherapy for refractory pediatric glaucoma. Ophthalmology. 1998 Oct;105(10):1921-6; discussion 1926-7. (1998) Abstract

Portellos M, Buckley EG, Freedman SF. Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma. J AAPOS. 1998 Feb;2(1):43-7. (1998) Abstract

Enyedi LB, Peterseim MW, Freedman SF, Buckley EG. Refractive changes after pediatric intraocular lens implantation. Am J Ophthalmol. 1998 Dec;126(6):772-81. (1998) Abstract

Bock CJ, Freedman SF, Buckley EG, Shields MB. Transscleral diode laser cyclophotocoagulation for refractory pediatric glaucomas. J Pediatr Ophthalmol Strabismus. 1997 Jul-Aug;34(4):235-9. (1997) Abstract

Freedman SF, Kylstra JA, Capowski JJ, Realini TD, Rich C, Hunt D. Observer sensitivity to retinal vessel diameter and tortuosity in retinopathy of prematurity: a model system. J Pediatr Ophthalmol Strabismus. 1996 Jul-Aug;33(4):248-54. (1996) Abstract

Hall JG, Freedman SF, Kylstra JA. Clinical course and systemic correlates of retinopathy of prematurity in quintuplets. Am J Ophthalmol. 1995 May;119(5):658-60. (1995) Abstract

Capowski JJ, Kylstra JA, Freedman SF. A numeric index based on spatial frequency for the tortuosity of retinal vessels and its application to plus disease in retinopathy of prematurity. Retina. 1995;15(6):490-500. (1995) Abstract

Freedman SF, Freedman NJ, Shields MB, Lobaugh B, Samsa GP, Keates EU, Ollie A. Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level. Am J Ophthalmol. 1993 Nov 15;116(5):600-11. (1993) Abstract