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Physicians

John H.P. Alexander, MD, MHS

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  • Duke Health Center at Southpoint

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  • Consultative Heart Care Imaging
  • Critical Care

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John H.P. Alexander, MD, MHS

Department / Division
Medicine / Medicine - Cardiology

Address
DUMC 3300
Durham, NC 27710

Appointment Telephone
919-681-5816

Office Telephone
919-681-5816

Fax Telephone
919-681-0811

Training
  • MD, University of Pennsylvania School of Medicine, 1993

Residency
  • Internal Medicine, Brigham and Women's Hospital (Massachusetts), 1993-1996

Fellowship
  • Cardiovascular Disease, Duke University Medical Center, 1996-2000

Other Training
  • MHS, Duke University, 2001

Clinical Interests
General adult cardiology, acute and general cardiovascular disease, coronary artery disease, chest pain, unstable angina, myocardial infarction, acute coronary syndromes, heart failure, hypertension, echocardiography, transesophageal echocardiography, stress echocardiography, valvular heart disease

Research Interests
My major research interests are in the pathyophysiology and therapeutics of acute coronary syndromes and chronic coronary artery disease with a particular interest in clinical research in cardiac surgery. Methodologically, I focus on early phase clinical research and site based research techniques.

Industry Relationships and Collaborations (What's this?)

This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

  • Bayer Healthcare
  • Boeringer Ingelheim
  • Bristol Myers Squibb
  • CLS Behring
  • Daiichi Sankyo
  • Janssen Pharmaceuticals (Johnson & Johnson)
  • Moerae Matrix
  • Novartis
  • Orexigen Therapeutics, Inc.
  • Pfizer Inc.
  • Regado Biosciences
  • Somahlution
  • Xoma Pharmaceuticals

Representative Publications
Serebruany, VL; Malinin, AI; Callahan, KP; Binbrek, A; Van De Werf, F; Alexander, JH; Granger, CB; Gurbel, PA; Assessment of the Safety and Efficacy of a New Thrombolytic Agent platelet substudy. Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy. American Heart Journal. 2003;145:636-642. (2003) Abstract

Akkerhuis, KM; Alexander, JH; Tardiff, BE; Boersma, E; Harrington, RA; Lincoff, AM; Simoons, ML. Minor myocardial damage and prognosis: are spontaneous and percutaneous coronary intervention-related events different?. Circulation. 2002;105:554-556. (2002) Abstract

Al-Khatib, SM; Califf, RM; Hasselblad, V; Alexander, JH; McCrory, DC; Sugarman, J. Medicine. Placebo-controls in short-term clinical trials of hypertension. Science. 2001;292:2013-2015. (2001) Abstract

Angeja, BG; Alexander, JH; Chin, R; Li, X; Barron, HV; Armstrong, PW; Granger, CB; Van de Werf, F; Gibson, CM. Safety of the weight-adjusted dosing regimen of tenecteplase in the ASSENT-Trial. American Journal of Cardiology. 2001;88:1240-1245. (2001) Abstract

Callahan, KP; Malinin, AI; Gurbel, PA; Alexander, JH; Granger, CB; Serebruany, VL. Platelet function and fibrinolytic agents: two sides of a coin?. Cardiology: international journal of cardiovascular medicine, surgery and pathology. 2001;95:55-60. (2001) Abstract

Alexander, JH; Sparapani, RA; Mahaffey, KW; Deckers, JW; Newby, LK; Ohman, EM; Corbalan, R; Chierchia, SL; Boland, JB; Simoons, ML; Califf, RM; Topol, EJ; Harrington, RA. Association between minor elevations of creatine kinase-MB level and mortality in patients with acute coronary syndromes without ST-segment elevation. PURSUIT Steering Committee. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy. JAMA: Journal of the American Medical Association. 2000;283:347-353. (2000) Abstract

Patel, M; Han, SS; Vaux, K; Saalfeld, J; Alexander, JH. A protocol of early spiral computed tomography for the detection of stones in patients with renal colic has reduced the time to diagnosis and overall management costs. ANZ Journal of Surgery. 2000;70:39-42. (2000) Abstract

Alexander, JH; Al-Khatib, S; Cantor, W; Greenbaum, AB; Hudson, MP; Kong, DF; Shah, M. Highlights from the American College of Cardiology 48th Annual Scientific Sessions: March 7 to 10, 1999. American Heart Journal. 1999;138:175-190. (1999) Abstract

Alexander, JH; Granger, CB; Sadowski, Z; Aylward, PE; White, HD; Thompson, TD; Califf, RM; Topol, EJ. Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators. American Heart Journal. 1999;137:799-805. (1999) Abstract

Alexander, JH; Harrington, RA; Tuttle, RH; Berdan, LG; Lincoff, AM; Deckers, JW; Simoons, ML; Guerci, A; Hochman, JS; Wilcox, RG; Kitt, MM; Eisenberg, PR; Califf, RM; Topol, EJ; Karsh, K; Ruzyllo, W; Stepinska, J; Widimsky, P; Boland, JB; Armstrong, PW. Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes. PURSUIT Investigators. Platelet IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy. American Journal of Cardiology. 1999;83:1147-1151. (1999) Abstract

Alexander, JH; Kong, DF; Cantor, WJ. Highlights from the 71st American Heart Association Scientific Sessions: November 8 to 11, 1998. American Heart Journal. 1999;137:555-574. (1999) Abstract

Pertusi, RM; Godwin, KS; House, JK; Knebl, JA; Alexander, JH; Rubin, BR; Forman, MD. Gastropathy induced by nonsteroidal anti-inflammatory drugs: prescribing patterns among geriatric practitioners. JAOA: Journal of the American Osteopathic Association. 1999;99:305-310. (1999) Abstract

Sadowski, ZP; Alexander, JH; Skrabucha, B; Dyduszynski, A; Kuch, J; Nartowicz, E; Swiatecka, G; Kong, DF; Granger, CB. Multicenter randomized trial and a systematic overview of lidocaine in acute myocardial infarction. American Heart Journal. 1999;137:792-798. (1999) Abstract

Alexander, JH; Alexander, K; Kong, DF; Tung, CY; Whellan, D. Session highlights from the American Heart Association Scientific Sessions: November 9-12, 1997. American Heart Journal. 1998;135:157-180. (1998) Abstract

Alexander, JH; Greenbaum, AB; Hudson, MP; Kong, DF; Miller, JM; Tung, CY; Whellan, DJ. Session highlights from the American College of Cardiology Scientific Sessions: March 29 to April 1, 1998. American Heart Journal. 1998;135:1099-1114. (1998) Abstract

Alexander, JH; Greenbaum, AB; Hudson, MP; Kong, DF; Miller, JM; Tung, CY; Whellan, DJ. Session highlights from the American College of Cardiology Scientific Sessions: March 29 to April 1, 1998. American Heart Journal. 1998;136:176-179. (1998) Abstract

Alexander, JH; Harrington, RA. Recent antiplatelet drug trials in the acute coronary syndromes. Clinical interpretation of PRISM, PRISM-PLUS, PARAGON A and PURSUIT. Drugs. 1998;56:965-976. (1998) Abstract

O'Neill, GF; Alexander, JH. Spontaneous bladder rupture in a patient with widespread superficial transitional cell carcinoma. ANZ Journal of Surgery. 1998;68:79. (1998) Abstract

Alexander, JH; Harrington, RA. Adjunctive Antiplatelet Therapy in Acute Myocardial Infarction: The Road to Improved Infarct-Related Artery Patency. Journal of Thrombosis and Thrombolysis. 1997;4:353-355. (1997) Abstract

Alexander, JH; Harrington, RA. Antiplatelet and antithrombin therapies in the acute coronary syndromes. Current Opinion in Cardiology. 1997;12:427-437. (1997) Abstract

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About This Page

Updated: Sept. 7, 2011
Published: Dec. 12, 2006
URL: http://www.dukehealth.org/physicians/john_h_p_alexander