Pfizer C440 - Clinical Trial

Email to Participate

paula.h.lee@duke.edu

What is the Purpose of this Study?

We are doing this study to find out if the study drug is safe and to determine the most effective dose of the study drug.

What is the Condition Being Studied?

Advanced or metastatic tumors

Who Can Participate in the Study?

Adults with solid tumors, including:
-Non-small cell lung carcinoma (NSCLC)
-Squamous cell carcinoma of the head and neck (SCCHN)
-Ovarian cancer
-Other types of cancer that the study doctor believes may be treated with this drug.

Age Group

Adults

What is Involved?

If you choose to join this study, you will:
-Receive injections or infusions of the study drug, once every 2 weeks
-Have a tumor biopsy or provide old tumor tissue
-Provide blood samples
-Have physical exams, blood and urine tests
-Have imaging scans (CT and/or MRI)
-Have heart tests (ECG)

Study Details

Full Title

A Phase 1 Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of PF-07257876 in patients with Advanced or Metastatic Tumors

Principal Investigator