BRAVO study - Broad spectrum Rapid Antidote: Varespladib Oral for snakebite - Clinical Trial

Email to Participate

What is the Purpose of this Study?

We are doing this study to see how an investigational drug, Varespladib, works in your body and against symptoms from snake venom.

What is the Condition Being Studied?

Snake bites

Who Can Participate in the Study?

Adults who:
- Have been bitten by a venomous snake
- Are having symptoms

Age Group

Adults

What is Involved?

If you choose to be in this study, you will:
- Be randomly assigned (like flipping a coin) to 1 of 2 groups
-- Group 1: Take the study drug by mouth for 7 days
-- Group 2: Take a placebo (harmless, inactive substance) by mouth for 7 days
- Have physical exams, blood draws, and urine tests
- Have electrocardiograms (ECG), scans to look at your heart
- Complete surveys about your symptoms and recovery

Study Details

Full Title

Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of a Multi-Dose Regimen of Oral Varespladib-Methyl in Subjects Bitten by Venomous Snakes

Principal Investigator