ACTIV-1 IM - Clinical Trial
What is the Purpose of this Study?
We are doing this study to test the ability of various drugs to improve health outcomes for people with COVID-19.
Who Can Participate in the Study?
Adults currently hospitalized with severe COVID-19 complications
What is Involved?
If you choose to join this study, you will:
--Be randomized to 1 of 3 Groups:
---Group 1 will test the study drug Abatacept vs. placebo (infusion into your vein)
---Group 2 will test the study drug Infliximab vs. placebo (infusion into your vein)
---Group 3 will test the study drug Cenicriviroc vs. placebo (60 days of pills)
-Give blood samples
-Participate in clinic and phone visits following discharge from hospital
-All patients will also get Remdesivir
*A placebo is a harmless inactive treatment that does not have medicine in it