Project CHI: an MRI Study - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about how the immune system affects the brain, and how this in turn may affect the way we think and behave. We are also interested in how HIV disease may alter the immune system, and if marijuana use alters these processes. For this study, we are including participants with or without HIV who do or do not use marijuana.

What is the Condition Being Studied?

Cognitive Function

Who Can Participate in the Study?

Men who:
- Are ages 25-55
- Are native English speakers

For more information about who can be in this study, please contact the study team at or 919-681-4442.

Age Group

What is Involved?

If you choose to join this study, you will complete up to 4 study visits over 2 years. Activities during these visits will include:
- Interviews with our staff
- Cognitive testing
- Blood draws
- MRI of the brain

The study does not involve the use of any drugs, and you will not have to make any lifestyle changes. Joining this study will not prevent you from joining other studies at Duke or anywhere else.

For more information, please visit our website:

Study Details

Full Title
Modeling the effects of chronic marijuana use on neuroinflammation and HIV-related neuronal injury
Principal Investigator
Christina Meade
Protocol Number
IRB: PRO00106797
NCT: NCT04810858
Phase N/A
Enrollment Status
Open for Enrollment
Contact the Duke Recruitment Innovation Center