STICk-IM (Lung Cancer with Brain Metastases) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to find out if the timing of radiation and immunotherapy can improve outcomes.
Lung cancer that has spread to the brain
Who Can Participate in the Study?
Adults ages 18 and older who:
- Have between 1-15 brain metastases
- Primary tumor origin is non-small cell lung cancer
- Plan to have immunotherapy
- Are able to have an MRI
- Have not received whole brain radiation therapy
What is Involved?
If you choose to join this study, you will:
- Be randomized (like flipping a coin) into Group 1 or Group 2:
-- Group 1 will go as follows:
--- Have stereotactic radiation therapy (SRS) right away in up to 5 doses
--- Receive immunotherapy later after the SRS
-- Group 2 will go as follows:
---- Receive immunotherapy right away
---- Receive SRS later, but only if your cancer progresses
All study participants will:
- Answer questionnaires
- Have neurocognitive tests
- Have blood draws
Your participation will last for about 1 year. You may be asked to come for one more visit between year 1 and year 2, but only if your cancer progresses.