Therapeutics for Inpatients with COVID-19 (TICO)/ACTIV-3 - Clinical Trial
What is the Purpose of this Study?
This research study is looking at a new investigational drugs to see if they can help people with COVID-19 get better and go home faster.
Who Can Participate in the Study?
Adults who have tested positive for COVID-19 within the last 3 days and need to be admitted to the hospital.
What is Involved?
If you agree to be in this study, you will:
-Be randomly assigned to 1 of 4 groups
---Groups 1, 2, and 3 will get a dose of a study drug through a vein in your arm (This means you have 3 out of 4 possibility to get a study drug)
---Group 4 will get a placebo (harmless saline with no medicine) through a vein in your arm
-Both groups will:
-Get Remdesivir (an antiviral medication being used to treat COVID-19)
-Have a nasal swab collected
-Have blood samples taken up to 5 times in the first 3 months of the study.
-Allow the study team to review your medical information for up to 1 year after the study is finished