ACT in HCT (Stem Cell Transplant) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if a new treatment strategy called acceptance and commitment therapy (ACT) can help reduce unwanted physical and psychological outcomes after allogeneic stem cell transplant.

What is the Condition Being Studied?

Allogeneic (Donor) Stem Cell Transplant

Who Can Participate in the Study?

Adults ages 18-80 who:
- Are scheduled to get an allogeneic stem cell transplant for any type of illness
- Are English-speaking
- Have a caregiver who is willing to participate with them

For more information about who can join this study, please contact the study team at hilary.miller299@duke.edu or 919-668-7238.

What is Involved?

If you choose to join the study, you will:
- Participate in acceptance and commitment therapy (ACT)
- Complete physical function and cognitive function tests
- Fill out questionnaires
- Use an iPhone and Apple Watch to track your activity (these items can be provided)
- Give stool samples
- Have your skin swabbed
- Have blood draws

If your caregiver chooses to join the study, they will:
- Also participate in acceptance and commitment therapy (ACT)
- Fill out questionnaires
- Give stool samples
- Have your skin swabbed
- Have blood draws

Study Details

Full Title
ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients
Principal Investigator
Cellular Therapy Specialist
Protocol Number
IRB: PRO00105683
NCT: NCT04423939
ClinicalTrials.gov
Enrollment Status
Open for Enrollment
Participate
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698