Nanospectra Nanoparticle Laser Therapy for Prostate Cancer - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about an investigational therapy that will use thermal (heat) in attempt to destroy prostate cancer cells and tumors.

What is the Condition Being Studied?

Prostate Cancer

Who Can Participate in the Study?

Adults, 45+ who:
-Have prostate cancer
-Have a Gleason score less than or equal to 7
-No evidence of metastatic disease
-PSA less than 15 ng/ml
-Have any other health conditions that may jeopardize ability to participate in the study

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
-Get an infusion of study material (gold nanoparticles)
-investigational laser will be applied to your tumor (with the goal of exciting the gold particles and producing heat that could help kill cancer cells).
-fill out questionnaires
-have biopsies
-have blood draws including for PSA measurement
-have follow-up MRIs 6 and 12 months after laser therapy to assess your tumor
-have follow-up data collected about you for up to 5 years.

Total active participation in the study will last approximately 1 year with additional follow-up information collected for up to a further 5 years.

Study Details

Full Title
An Extension Study of MRI/US Fusion Imaging and Biopsy in Combination with Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue
Principal Investigator
Surgical Oncologist
Protocol Number
IRB: PRO00105492
NCT: NCT04240639
Phase
Phase III
ClinicalTrials.gov
Enrollment Status
Open for Enrollment
Participate
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698