HERO HCQ Trial - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn if taking hydroxychloroquine (HCQ) helps prevent COVID-19 infection in health care workers compared to placebo.

What is the Condition Being Studied?

COVID-19 Prevention

Who Can Participate in the Study?

Any adult working in a facility that delivers healthcare, including, but not limited to:
-Physician Assistants
-Nurse Practitioners
-Environmental Service workers
-Patient Transporters
-Food Service workers
-Emergency services personnel
-Physical therapists
-Speech pathologists

Age Group

What is Involved?

To participate in this trial, you will first join the HERO Registry. After you join the Registry, you will be asked if you would like to receive information about the HERO-HCQ trial .

If you qualify for this trial , you will:
- Be randomized to Study Group 1 or Study Group 2
-- Group 1 will receive hydroxychloroquine
-- Group 2 will receive placebo (a harmless pill with no therapeutic effect)
- You will be asked to give a blood sample
- A nasal swab will be collected to check for the virus

Learn more about the HERO-HCQ Trial and the HERO Registry at:

Study Details

Full Title
Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine Trial (HERO HCQ Trial)
Principal Investigator
Infectious Disease Specialist
Protocol Number
IRB: PRO00105376
Phase III
Contact the Duke Recruitment Innovation Center