Pragmatic trial of hydroxychloroquine/azithromycin for COVID - Clinical Trial

What is the Purpose of this Study?

If you choose to join this study, you will:
- Be randomized (like picking numbers out of hat) to 1 of 4 goups
--Group 1 will get 5 days of Hydroxychloroquine alone
--Group 2 will get 5 days of Azithromycin alone
--Group 3 will get 5 days of Hydroxychloroquine and Azithromycin
--Group 4 will have 5 days of no study drug

What is the Condition Being Studied?


Who Can Participate in the Study?

Adults and children over 12 years old:
- Have been diagnosed with COVID-19
- Are currently in the hospital

Age Group
Adults, Children

What is Involved?

We are doing this study to learn more about the study drugs (Azithromycin and
Hydroxychloroquine), and to see if they might help people who are infected with the virus.

Study Details

Full Title
Pragmatic Factorial Trial of Hydroxychloroquine, Azithromycin, or both for treatment of severe SARS-CoV-2 Infection
Principal Investigator
Infectious Disease Specialist
Protocol Number
IRB: PRO00105339
NCT: NCT04335552
Phase II
Contact the Duke Recruitment Innovation Center