ARTACUS (Skin Cancers in Organ Transplant Recipients) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about the effects of an experimental drug called RP1 (the study drug) for organ transplant recipients who have an advanced form of skin cancer.

What is the Condition Being Studied?

Advanced Skin Cancer in Organ Transplant Recipients

Who Can Participate in the Study?

Adults ages 18+ who:

Have received a liver, kidney, heart, lung, or other solid organ transplant
Are diagnosed with an advanced form of skin cancer
Have a tumor large enough to receive and injection
Have stable transplant status

For more information about who can join this study, please contact the study team at erin.campo@duke.edu.

Age Group

Adults

What is Involved?

If you join this study, you will:

Be treated with the study drug for 1 year (the study drug is given as injections directly into tumors)
Return to the clinic for follow-up visits for 2 years after you finish taking the drug
Have physical exams
Answer questionnaires
Have electrocardiograms (ECG) performed
Have tumor biopsies done
Give blood samples
Have MRI and CT scans