Safety and efficacy of CGX1321 +/- pembrolizumab for advanced tumors - Clinical Trial
What is the Purpose of this Study?
We are doing this study to see if the study drug, CGX1321, is safe and effective for fighting cancer.
Who Can Participate in the Study?
Adults with advanced gastrointestinal cancer who:
-Failed, refused, or are unsuited for standard-of-care treatment
What is Involved?
If you choose to join this study, you will:
-Take the study drug, CGX1321, by mouth once a day
-Take zoledronic acid by I.V. once every 6 or 8 weeks
-Take daily supplements of vitamin D3 and calcium carbonate
-Give blood and urine samples
-Have regular CT or MRI scans
In addition, some people may also get pembrolizumab by I.V. once every 3 weeks.