GVHD prophylaxis in Peripheral Blood Stem Cell Transplantation - Clinical Trial
What is the Purpose of this Study?
We are doing this study to find out whether one medication (Tacrolimus/methotrexate) is better than another medication(Tacrolimus/mycophenolate mofetil/cyclophosphamide) in preventing graft-versus-host disease (GVHD).
Graft versus- host disease (GVHD)
Who Can Participate in the Study?
Adults that are undergoing allogeneic PBSC transplant for the treatment of acute leukemia and chronic myelogenous leukemia.
What is Involved?
If you choose to be in the study you will be asked to go through a medical screening that includes a physical, a heart test (EKG and Echo) a breathing test, and potentially a bone marrow biopsy.
If still eligible you will be asked to:
-Take the study medication as directed
-Continue treatment as you would with any transplant