Call your doctor before leaving home if you think you’ve been exposed to COVID-19 or have symptoms

Due to the presence of COVID-19 in our community, visitor restrictions are in place for all Duke clinics and hospitals. For your safety and the safety of others, we recommend patients do not bring a visitor to Duke clinics, if at all possible. If a visitor must accompany a patient, only one individual over 12 years of age is allowed. Patients and visitors will be screened for symptoms upon arrival. Individuals with flu-like symptoms are not allowed. View the complete list of Visitor Restrictions.

Effective immediately, Duke Health is prioritizing and rescheduling some non-emergent or non-critical surgeries, procedures, and appointments. Check our COVID-19 (Coronavirus) page for updates.

DMID 16-0058 - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn more about the study drug (ZTI-01) and its ability to be a potential antibiotic to be used to treat bacterial lung infections.
What is the Condition Being Studied?
Healthy Volunteers to treat Bacterial Lung Infection

Who Can Participate in the Study?

- Men and Women 18-45
- Are healthy
- Non-smokers
- Do not use medications, with the exception of birth control

Age Group

What is Involved?

If you choose to join this study, you will:
- Complete 1 outpatient screening visit
- Complete a 3-day inpatient admission to the Duke Early Phase Research Unit
- Have 1 follow-up phone call

Study Details

Full Title
A Phase 1 Safety and Intrapulmonary Pharmacokinetics Study of ZTI-01 (Intravenous Fosfomycin Disodium) in Healthy Adult Subjects
Principal Investigator
Pulmonologist
Protocol Number
IRB: PRO00101916
NCT: NCT03910673
Phase
Phase I
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698