SELECT Study: for Obesity - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn if semaglutide can lower your chance of having a heart attack or stroke in the future if you have already had a heart attack, stroke, or been diagnosed with peripheral arterial disease (PAD).
What is the Condition Being Studied?
Cardiovascular and Peripheral Artery Disease

Who Can Participate in the Study?

Men or Women who are:
- 45 years old or older
- Overweight
- Have had a heart attack, stroke, or have been told you have peripheral arterial disease (PAD)
- Do not have diabetes

Age Group

What is Involved?

If you qualified to participate you will be randomized (like the flip of a coin) to receive either the study medicine or a placebo. As part of your study participation you will receive:
- Study-related care, including regular health check-ups
- Guidance on healthy lifestyle choices

Study Details

Full Title
SELECT Study - Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity
Principal Investigator
Protocol Number
IRB: PRO00101005
NCT: NCT03574597
Phase III
Contact the Duke Recruitment Innovation Center