GOG3018 OVAL (Ovarian Cancer) - Clinical Trial
What is the Purpose of this Study?
Who Can Participate in the Study?
Adult females with platinum resistant ovarian cancer who are willing to have biopsies as needed per study protocol.
What is Involved?
If you agree to be in this study, you will:
-Be randomized, like drawing numbers out of a hat, to one of two different drug options:
--- Group A will receive VB-111 infusion once every 2 months
--- Group B will receive a placebo (salt water solution with no active drug) once every two months
- Everyone will:
- Receive weekly IV infusions of pacltaxel
- Have biopsies one month after the first dose of the study drug and two weeks after the third dose of study drug
- Visit the clinic every 56 days for a physical and blood work
- Continue on the study as long as your cancer does not get worse and you do not have bad effects
- Long-term follow up will continue every 3 months for up to 5 years